Protein Alignment CG7246 and Utp6

DIOPT Version :9

• Sequence 1: NP_572520.1
• Gene: CG7246 / 31833
• FlyBaseID: FBgn0030081
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_659075.1
• Gene: Utp6 / 216987
• MGIID: 2445193
• Length: 597
• Species: Mus musculus
• Alignment Length: 625
• Identity: 162/625 - (25%)
• Similarity: 284/625 - (45%)
• Gaps: 55/625 - (8%)

  Fly     1 MAEFIAEMQERLLPEYEQMKNYSVFTADQVREIVSRRERLFLKINKSHQSITDYLDFILYEKHMH 65
            |||.|.|..|..:||.||::...:|:..:::.|:.:...|..||::......|:::::.||.::
Mouse     1 MAEIIQERIEDRIPELEQLERIGLFSHAEIKAIIKKASDLEYKIHRRTLLKEDFINYVQYEINL- 64

  Fly    66 MTIVDKEK---KMHVKLTGLKASIATRIMRLYREALAKFNHDRRLWSNWIKFSRK-SNPVEVAGI 126
            :.::.:.:   |...|...::.|:..|:..::..|.||:..|.:||.::|.|.:| .....::.|
Mouse    65 LELIQRRRARIKYSFKKDEIEYSMVHRVQGVFGRASAKWKDDVQLWLSYIVFCKKWGTKTHLSKI 129

  Fly   127 YEKMLLYHGDSPDLWVDAALWLYEFNRLNIDRVKDILLRGLQRHPDSEALNKCFFDIMLKEAALA 191
            :..||..|.:.|.||:.||.|..| :||:.:..:.:.||.|:.||:...|.:.:|.:.|..|...
Mouse   130 FSAMLAIHSNKPALWIMAAKWEME-DRLSSESARQLFLRALRFHPECPKLYQEYFRMELMHAEKL 193

  Fly   192 SNERNLAENTL--------SEQDIKLERVEAVYRNSMANITQLDYFVKLLESCEDHQELTGKLQR 248
            ..|:...|...        .|:.:|.|....:|:||::.|...::.|.||...:.. :....||:
Mouse   194 RKEKQEFEKAAMDMGDFDHPEEILKGELARIIYKNSISKIKGAEFHVSLLAIAQLF-DFAKDLQK 257

  Fly   249 MIIDDMQEKFPREPGLWDLLAQRELRGFHLGDLEEEDLDTSDEEPASKKSRSVNGRSLKRRIQLC 313
            .|.||:|.....:|..||.:|:|||         |.:....:|:|.||::::|   .:.||.:.|
Mouse   258 EIYDDLQALHTDDPLTWDYVARREL---------EIESQPGEEQPVSKQAKAV---EMGRREERC 310

  Fly   314 VTVYKSAVEELQTTEMWNMYLDAMLALNSDGKTERILKQQCLAD---ALQAGHRSQLMGVKHYAT 375
            ..||:.||:.|.|..||..|:...|...|...:...|:.|.|..   |.:..|..:|:....|..
Mouse   311 CAVYEEAVKALPTEAMWKCYITFCLERFSKKTSSVPLRGQRLERTMLAFRKAHELKLLSEVQYKQ 375

  Fly   376 LRKMLCTAPSGREA--AVTILTEALKNDSSVEMHELLLATHIQS---DSEPLIYELFNKIQKSMG 435
            ...:|......:||  .....||..|:  ||.|.:..|...|.|   |.|....|.|..::..:
Mouse   376 WIDLLLRQDLFKEALQVAEAGTELFKD--SVTMWQTKLQVLIDSKSPDVEMRFEEAFAHLKPQV- 437

  Fly   436 SEALPLWRSVILYYRTRQDSLGARRLDEIYGLACKAAWPEFG----ELRSDYLRYLWQERSVEEA 496
              .||||.|      ..:.|..|:..::...:..||.....|    .|:..||.:.::....::|
Mouse   438 --CLPLWIS------WAEWSESAKSQEDTEAIFKKAIIAVTGASSVTLKEKYLDWAYRSGGYKKA 494

  Fly   497 RKEYAKLAILPPMSLALHRQMVQLESSAAACDQASLKYWRMCYDFMACYFGKTQPRVWVEYLAFE 561
            |..:..|....|.|:...|:|:|.|.....|...:|:.:   |:.....||.:...:|::|:..|
Mouse   495 RAVFKSLQESRPFSVEFFRKMMQFEKEQEPCKMVNLREY---YERALREFGTSDSDLWMDYIKEE 556

  Fly   562 RDH--GEAKNISLLTQRALSTLEPQYVAAFEAERALAYVG 599
            .:|  |:.:|...:..||:..|:.|....|.|:.|:...|
Mouse   557 LNHPFGKPENCGQIYWRAMKMLQGQSAELFVAKHAMHQAG 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7246	NP_572520.1	COG5191	1..>261	CDD:227518	71/271 (26%)
		U3_assoc_6	10..>62	CDD:285803	12/51 (24%)
Utp6	NP_659075.1	COG5191	1..>222	CDD:227518	58/222 (26%)
		U3_assoc_6	9..81	CDD:285803	14/72 (19%)
		HAT 1	121..153		10/31 (32%)
		HAT 2	156..188		8/31 (26%)
		HAT 3	304..335		12/30 (40%)
		HAT 4	488..520		8/31 (26%)
		HAT 5	524..557		7/35 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837767
Domainoid	1	1.000	150	1.000	Domainoid score	I4387
eggNOG	1	0.900	-	-		E1_COG5191
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41265
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3954
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55709
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005618
OrthoInspector	1	1.000	-	-		oto93060
orthoMCL	1	0.900	-	-		OOG6_102475
Panther	1	1.100	-	-	LDO	PTHR23271
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1623
SonicParanoid	1	1.000	-	-		X4593
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790