DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15365 and N4bp3

DIOPT Version :9

Sequence 1:	NP_001285030.1	Gene:	CG15365 / 31829	FlyBaseID:	FBgn0030077	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	NP_001029065.1	Gene:	N4bp3 / 303112	RGDID:	1308356	Length:	537	Species:	Rattus norvegicus

Alignment Length:	570	Identity:	134/570 - (23%)
Similarity:	224/570 - (39%)	Gaps:	106/570 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 GVGMGMGMGLQMRSKFQNIRQMFELSRSCVGGGGG----DG--RGGAAEEEAMQSLPATLPQQHQ 176
            |:.||....|..|..|..     |..|:.:.|..|    ||  |.|..:.|....|  .||::..
  Rat     9 GIAMGSVGSLLERQDFSP-----EELRAALAGSRGSRQPDGLLRKGLGQREFFSYL--HLPKKDG 66

  Fly   177 QQQQR--RTTPIAGGSRHQQQQQMGEAEQTS----GNF----LRPIAFKPIPFEPDYRIACQQQQ 231
            :..:|  |..|......:::..:.|:..:||    |.|    :||..|||       .::..:..
  Rat    67 KTAKRAPRNEPDYTTLYYREHPRAGDFSKTSLPERGRFDKCRIRPSVFKP-------PVSTGKGF 124

  Fly   232 QHQQQLQLQQQQQQQQQQQQQQQLQLQHQQQQQHQQQHQHQHQQQHQSLQLPTEGGQAGGVAAER 296
            ...|.|...:.|:..:.......|.. |.......:..|.:.|..| :|.| .|||....::...
  Rat   125 LSMQSLAAHKGQKLWRSNGSLHTLAC-HPPLSPGPRASQARAQLLH-ALSL-DEGGPEPSLSDSS 186

  Fly   297 YG--YGSTPSLAPLPTASAQKFGSTTDLRHLAARRRNHRLLQRCSNEDALTLDLLSTGSHDRPDG 359
            .|  :|.:|...|.|.:|     |...:.||.                         ||.||. .
  Rat   187 SGGSFGRSPGTGPSPFSS-----SLGHINHLG-------------------------GSLDRA-S 220

  Fly   360 ASSKSSGTVVGSSDLTPSPSDSGIS----ELEAALKDRDSELSYLRQAMEHNEKVIF-QVQKDKE 419
            .|.|.||.:...|.|...|.....|    |..|.|.|...||.  |...:.:....| ||.::::
  Rat   221 RSPKESGPLAVLSCLPEPPPPYEFSCPTTEEVAVLPDTCEELK--RDLGDQDVSNPFTQVLEERQ 283

  Fly   420 VYWEHETQRLRLFYEGQQRECQLKLRKMEQLLGLQQFQLKQHKLRQSEQVNRLQQQLDLARDSSQ 484
            ..|..|.:||   |..:..|...|..:.|:.|.||.|..:|.:.|..::: |.||.| .....:.
  Rat   284 RLWLSELKRL---YVDRLHEVAQKAERSERNLQLQLFMAQQEQRRLRKEL-RAQQGL-APEPRTS 343

  Fly   485 GLQQQVDALRHQLEDSEWRVCERNGEIALLKTQLKEAHLEINMKDHAIVSLKHSSNRSSSSSNSN 549
            |...:.|......|::.|.||::..||:|||.||:||..|:..|...|.|||.....|.:.:.:.
  Rat   344 GPPMEADPNARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQ 408

  Fly   550 SNK----------------------SCDTNTSQSQ------PKQQAKEEQQQQQHPELQQQQQQQ 586
            ..:                      ||:|:..:|:      ...:|:|..:|.:...||::.:.|
  Rat   409 DAELARLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGNEAREGAEQLRAELLQERLRGQ 473

  Fly   587 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLKQQHQPDQQQLQKIITLKD 636
            :|..:.:|::|..|:::::..:.|::.|......::.:|...|::..|::
  Rat   474 EQALRFEQERQTWQEEKERVLRYQREIQGSYMDMYRRNQALEQELRVLRE 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15365	NP_001285030.1	Syntaphilin	<486..>518	CDD:291936	10/31 (32%)
N4bp3	NP_001029065.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..234		21/92 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..359		7/33 (21%)
		Fez1	361..518	CDD:284284	37/156 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	422..456		5/33 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000