Protein Alignment CG15365 and Lzts3

DIOPT Version :10

• Sequence 1: NP_001285030.1
• Gene: CG15365 / 31829
• FlyBaseID: FBgn0030077
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_008760370.1
• Gene: Lzts3 / 280670
• RGDID: 631327
• Length: 750
• Species: Rattus norvegicus
• Alignment Length: 884
• Identity: 186/884 - (21%)
• Similarity: 318/884 - (35%)
• Gaps: 259/884 - (29%)

  Fly     2 SAATHMAMPAHAV-----VPPPGTPPVLGGSGCSNLSLPSGKRGHKRSVSLENNAPLALRSTPSM 61
            |..:||| ||...     :..|..|.:.|       ..|||       :.:.....|.:|:.|..
  Rat    43 SRESHMA-PADLASEGPKLEDPPAPHLFG-------KCPSG-------LIMAKLETLPVRADPGR 92

  Fly    62 G--------QSSLG--SPLLQFGQAAPGQGHSQGFHTGTLKSRQEQRRLSQKF------GSHSNL 110
            .        .:.||  .|.|..|....|..|:|.|...::.:|.........|      ||.:|.
  Rat    93 DPLLAFAPRPAELGPPDPRLTMGSVGGGVTHAQEFPMKSVGTRTGGGGSQGSFPGPRSSGSGTNR 157

  Fly   111 DDEGVG--IGVGMGMGMGLQMRSKFQNIRQMFELSRSCVGGGGGDGRGGAAEEEAMQSLPATLPQ 173
            :..|.|  ......:...|.:..:.:. ....::..:.||..||....|.:::         .|.
  Rat   158 ERPGPGRYPSEDKVLANSLYLNGELRG-SDHTDVCGNVVGSSGGSSSSGGSDK---------APP 212

  Fly   174 QHQQQQ---QRRTTPIAGGSRHQQQQQMGEAEQTSGNFLRPIAFKPIPFEPDYRIACQQQQQHQQ 235
            |:::..   :..||             .|:.:|.|...:||.||||:          ..:..|..
  Rat   213 QYREPNHPPKLLTT-------------SGKLDQCSEPLVRPSAFKPV----------VPKNFHSM 254

  Fly   236 QLQLQQQQQQQQQQQQQQQLQLQHQQQQQHQQQHQHQHQQQHQSLQLPTEGGQAGGVAAERYGYG 300
            | .|...|.....:.:|....|:...:               :|..:...||..||..::    .
  Rat   255 Q-NLCPPQTNGTPEGRQGPAGLKGGLE---------------KSRTMTPAGGSGGGGLSD----S 299

  Fly   301 STPSLAPLPTASAQKFGSTTDLRHLAARRRNHRLLQRCSN--------------EDALTLDLLST 351
            ...||..|||.      |::..:|||....:...:.|...              :|..|.|   :
  Rat   300 GRNSLTSLPTY------SSSYSQHLAPLSASTSHINRIGTPGYSSGGGGGGSGYQDLGTSD---S 355

  Fly   352 GSHDRPDGASSK------------SSGTVVGSSDLTPSPSDSGISELEAALKDRDSELSYLRQAM 404
            |......|:||.            .:|.:..::...|||| :.|.|||..|.:::.|::.||:::
  Rat   356 GRASSKSGSSSSMGRSGHLGSGEGGNGGLPFAACSPPSPS-ALIQELEERLWEKEQEVAALRRSL 419

  Fly   405 EHNEKVIFQVQKDKEVYWEHETQRLRLFYEGQQRECQLKLRKMEQLLGLQQFQLKQHKLRQSEQV 469
            |.:|..:.||.::::..||.|...||....|:.::...:.::.:|.|.||..:|:|.|.:..|:.
  Rat   420 EQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEA 484

  Fly   470 NRLQQQLDLARDSSQGLQQQVDALRHQLEDSEWRVCERNGEIALLKTQLKEAHLEINMKDHAIVS 534
            .:|.:|.:...|.....|::......::|:::|.||::.|||:|||.|||::..:::.|...||.
  Rat   485 AQLIRQREELEDKVAACQKEQADFLPRMEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVG 549

  Fly   535 LKHSSNRSSSSSNSNSNKSCDTNTSQSQPKQQAKEEQQQQQHPELQQQQQQQQQQQQQQQQQQQQ 599
            |:                                 .|.::....|:::::|
  Rat   550 LR---------------------------------SQLREGRASLREKEEQ-------------- 567

  Fly   600 QQQQQQQQQQQQQQQQQLKQQHQPDQQQLQKIITLKDQVIGALTSELAKLRKELSDLAIAHEYGE 664
                                           :::|:|    :..|:.|.|  |||:       ||
  Rat   568 -------------------------------LLSLRD----SFGSKQASL--ELSE-------GE 588

  Fly   665 EPCGRYTRLKQQLDNLNEICQKTRKYTTTSASPTAVASPAAQVAPPAPSPA--AHVATPSCAQEL 727
            .|               ..|.|      .:.:|..:..|...:|......|  ...|..:.|..|
  Rat   589 LP---------------PACLK------PALTPVDLVEPQEALASCESDEAKMRRQAGVAAAASL 632

  Fly   728 PKLDVLVQRLQLDQG--QGTQQTLDTLIEESTTYAEDIAKLRQKLDDFRLNLELEKRQWSAEKDK 790
            ..:|.     ::|.|  .||:    .|..|......::|..|:..:....:...|:|.|..||:|
  Rat   633 VSVDG-----EVDAGGEGGTR----ALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEK 688

  Fly   791 VLGYQKQLQAHYIQMYQK----LRCLDSAGAAVGQVEAT 825
            |:.||||||..|::|||:    .|.|...|||.|....|
  Rat   689 VIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGSSTPT 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15365	NP_001285030.1	Fez1	<735..812	CDD:462015	26/82 (32%)
Lzts3	XP_008760370.1	COG4913	<396..>575	CDD:443941	52/260 (20%)
		Fez1	515..715	CDD:462015	66/320 (21%)