Protein Alignment CG15365 and Lzts1

DIOPT Version :10

• Sequence 1: NP_001285030.1
• Gene: CG15365 / 31829
• FlyBaseID: FBgn0030077
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_703200.1
• Gene: Lzts1 / 266711
• RGDID: 708565
• Length: 601
• Species: Rattus norvegicus
• Alignment Length: 785
• Identity: 156/785 - (19%)
• Similarity: 257/785 - (32%)
• Gaps: 276/785 - (35%)

  Fly    81 GHSQGFHTGTLKSRQEQRRLSQKFGSHSNLDDEGVGIGVGMGMGMGLQMRSKFQNIRQMF--ELS 143
            |||  .|:...::.|.:.|.|......:...|..:..|.....|.| :..||.......|  ::|
  Rat    10 GHS--LHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGRG-KSSSKMGKSEDFFYIKVS 71

  Fly   144 RSCVGGGGGD----GRGGAAEEEAMQSLPATLPQQHQQQQQRRTTPIAGGSRHQQQQQMGEAEQT 204
            :...|....|    ..|....:..:...|||.|         :..|.:      .|.:|...:..
  Rat    72 QKARGSHRPDYTALSSGDMGGQTGVDFDPATPP---------KLMPFS------SQLEMSSDKAA 121

  Fly   205 SGNFLRPIAFKPIPFEPDYRIACQQQQQHQQQLQLQQQQQQQQQQQQQQQLQLQHQQQQQHQQQH 269
                :||.||||:                                       |.......|....
  Rat   122 ----VRPTAFKPV---------------------------------------LPRSGAILHSSPE 143

  Fly   270 QHQHQQQHQSLQLPTE----GGQAGGVAAE--RYGYGSTPS--------LAPL--PTASAQKFGS 318
            ...||........|.|    .|...|..::  |....|.|:        |.||  |.....:||.
  Rat   144 STNHQLHPMPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTTSSYQLDPLVTPVGPTSRFGG 208

  Fly   319 TTDLRHLAARRRNHRLLQRCSNEDALTLDLLSTGSHDRPDGASSKSSGTVVGSSDLTPSP---SD 380
            :.           |.:.|....:|:..:.|.:....|  .|:.....|.|...|....||   .:
  Rat   209 SA-----------HNITQGIILQDSNMMSLKALSFSD--GGSKLAHPGKVEKGSSCVRSPLSTDE 260

  Fly   381 SGISELEAALKDRDSELSYLRQAMEHNEKVIFQVQKDKEVYWEHETQRLRLFYEGQQREC----- 440
            ..|.|||..|..|::.|..|:::.:..|....|.       :|...:|.|     .:.||
  Rat   261 CTIQELEQKLLQRETALQKLQRSFDEKEFASGQT-------FEERPRRTR-----DELECLEPKS 313

  Fly   441 -----QLKLRKMEQLLGLQQFQLKQHKLRQSEQVNRLQQQLDLARDSSQGLQQQVDALRHQLEDS 500
                 ..|.::.:|:|.||..||:|.|.:..:::..|.::.||.....:..:::.......||::
  Rat   314 KLKPASQKSQRTQQVLQLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTNFAPALEET 378

  Fly   501 EWRVCERNGEIALLKTQLKEAHLEINMKDHAIVSLKHSSNRSSSSSNSNSNKSCDTNTSQSQPKQ 565
            :|.||:::|||:|||.||||:.:|:|.|...|:||                            |.
  Rat   379 QWEVCQKSGEISLLKQQLKESQMEVNAKASEILSL----------------------------KA 415

  Fly   566 QAKEEQQQQQHPELQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLKQQHQPDQQQLQK 630
            |.|:.:.:.:..||:.|..:...:.:..:.:..:.:.|:::.:.:
  Rat   416 QLKDTRGKLEGMELKTQDLESALRTKGLELEVCENELQRKKNEAE-------------------- 460

  Fly   631 IITLKDQVIGALTSELAKLRKELSDLAIAHEYGEEPCGRYTRLKQQLDNLNEICQKTRKYTTTSA 695
               |..:.:..|..||.:||.:
  Rat   461 ---LLREKVNLLEQELLELRAQ------------------------------------------- 479

  Fly   696 SPTAVASPAAQVAPPAPSPAAHVATPSCAQELPKLDVLVQRLQLDQGQGTQQTLDTLIEESTTYA 760
              .|:...||.:.||                               |.|            .|::
  Rat   480 --AALHRDAAPLGPP-------------------------------GIG------------LTFS 499

  Fly   761 EDIAKLRQKLDDFRLNLELEKRQ---------------WSAEKDKVLGYQKQLQAHYIQMYQKLR 810
            |||..|:::||..|..|: |:||               |..||:||:.||||||..|:.|||:.:
  Rat   500 EDIPALQRELDRLRAELK-EERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYLAMYQRNQ 563

  Fly   811 CLDSA 815
            .|:.|
  Rat   564 RLEKA 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15365	NP_001285030.1	Fez1	<735..812	CDD:462015	29/91 (32%)
Lzts1	NP_703200.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	135..190		10/54 (19%)
		SMC_prok_B	<263..>467	CDD:274008	56/266 (21%)
		Fez1	378..570	CDD:462015	68/331 (21%)