DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15365 and N4BP3

DIOPT Version :10

Sequence 1:NP_001285030.1 Gene:CG15365 / 31829 FlyBaseID:FBgn0030077 Length:828 Species:Drosophila melanogaster
Sequence 2:NP_055926.1 Gene:N4BP3 / 23138 HGNCID:29852 Length:544 Species:Homo sapiens


Alignment Length:593 Identity:128/593 - (21%)
Similarity:222/593 - (37%) Gaps:145/593 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 GVGMGMGMGLQMRSKFQNIRQMFELSRSCVGGGGG----DG--RGGAAEEEAMQSLPATLPQQHQ 176
            |:.||....|..|..|..     |..|:.:.|..|    ||  |.|..:.|.:..|  .||::..
Human     9 GIAMGSVGSLLERQDFSP-----EELRAALAGSRGSRQPDGLLRKGLGQREFLSYL--HLPKKDS 66

  Fly   177 QQQQR-----RTTPIAGGS-RHQQQQQMGEAEQTS----GNF----LRPIAFKPIPFEPDYRIAC 227
            :..:.     |..|....: .:::..:.|:..:||    |.|    :||..|||........::.
Human    67 KSTKNTKRAPRNEPADYATLYYREHSRAGDFSKTSLPERGRFDKCRIRPSVFKPTAGNGKGFLSM 131

  Fly   228 QQQQQHQQQLQLQQQQQ----------QQQQQQQQQQLQLQHQQQQQHQQQHQHQHQQQHQSLQL 282
            |....|:.|...:....          ....:..|.:.||.|                   :|.|
Human   132 QSLASHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLH-------------------ALSL 177

  Fly   283 PTEGG----------QAGGVAAERYGYGSTPSLAPLPTASAQKFGSTTDLRHLAARRRNHRLLQR 337
             .|||          .:||      .:|.:|...|.|.:|     |...|.||.           
Human   178 -DEGGPEPEPSLSDSSSGG------SFGRSPGTGPSPFSS-----SLGHLNHLG----------- 219

  Fly   338 CSNEDALTLDLLSTGSHDRPDGASSKSSGTVVGSSDLTPSP----SDSGISELEAALKDRDSELS 398
                          ||.||......::....|.|....|.|    |.|...|:.|.|.:...|  
Human   220 --------------GSLDRASQGPKEAGPPAVLSCLPEPPPPYEFSCSSAEEMGAVLPETCEE-- 268

  Fly   399 YLRQAM--EHNEKVIFQVQKDKEVYWEHETQRLRLFYEGQQRECQLKLRKMEQLLGLQQFQLKQH 461
             |::.:  |.......||.::::..|..|.:||   |..:..|...|..:.|:.|.||.|..:|.
Human   269 -LKRGLGDEDGSNPFTQVLEERQRLWLAELKRL---YVERLHEVTQKAERSERNLQLQLFMAQQE 329

  Fly   462 KLRQSEQVNRLQQQLDLARDSSQGLQQQVDALRHQLEDSEWRVCERNGEIALLKTQLKEAHLEIN 526
            :.|..::: |.||.| .....:.|...:.|......|::.|.||::..||:|||.||:||..|:.
Human   330 QRRLRKEL-RAQQGL-APEPRAPGTLPEADPSARPEEEARWEVCQKTAEISLLKQQLREAQAELA 392

  Fly   527 MKDHAIVSLKHSSNRSSSSSNSNSNK----------------------SCDTNTSQSQ------P 563
            .|...|.|||.....|.:.:.:...:                      ||:|:..:|:      .
Human   393 QKLAEIFSLKTQLRGSRAQAQAQDAELVRLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAG 457

  Fly   564 KQQAKEEQQQQQHPELQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLKQQHQPDQQQL 628
            ..:|::..:|.:...||::.:.|:|..:.:|:::..|:::::..:.|::.|......::.:|...
Human   458 GSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQGGYMDMYRRNQALE 522

  Fly   629 QKIITLKD 636
            |::..|::
Human   523 QELRALRE 530

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15365NP_001285030.1 Fez1 <735..812 CDD:462015
N4BP3NP_055926.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 61..84 4/22 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 116..252 34/191 (18%)
YhaN 260..>438 CDD:443752 47/185 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 335..365 6/31 (19%)
Fez1 368..526 CDD:462015 35/157 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 430..465 5/34 (15%)
Blue background indicates that the domain is not in the aligned region.

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