Protein Alignment CG15365 and Lzts1

DIOPT Version :10

• Sequence 1: NP_001285030.1
• Gene: CG15365 / 31829
• FlyBaseID: FBgn0030077
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_955396.2
• Gene: Lzts1 / 211134
• MGIID: 2684762
• Length: 599
• Species: Mus musculus
• Alignment Length: 796
• Identity: 158/796 - (19%)
• Similarity: 253/796 - (31%)
• Gaps: 300/796 - (37%)

  Fly    81 GHSQGFHTGTLKSRQEQRRLSQKFGSHSNLDDEGVGIGVGMGMGMGLQMRSKFQNIRQMF--ELS 143
            |||  ||:...::.|.:.|.|......:...|..:..|.....|.| :..||.......|  ::|
Mouse    10 GHS--FHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGRG-KSSSKMGKSEDFFYIKVS 71

  Fly   144 RSCVGGGGGD----GRGGAAEEEAMQSLPATLPQQHQQQQQRRTTPIAGGSRHQQQQQMGEAEQT 204
            :...|....|    ..|....:..:...|||.|:......|...:...|.
Mouse    72 QKARGSHRPDYTALSSGDIGGQTGVDFDPATPPKLMPFSNQLEMSSDKGA--------------- 121

  Fly   205 SGNFLRPIAFKPIPFEPDYRIACQQQQQHQQQLQLQQQQQQQQQQQQQQQLQLQHQQQQQHQQQH 269
                :||.||||:                                       |.......|....
Mouse   122 ----VRPTAFKPV---------------------------------------LPRSGAILHSSPE 143

  Fly   270 QHQHQQQHQSLQLPTE----GGQAGGVAAE--RYGYGSTPS--------LAPL--PTASAQKFGS 318
            ...||........|.|    .|...|..::  |....|.|:        |.||  |.....:||.
Mouse   144 STSHQLHPMPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTTSSYQLDPLVTPVGPTSRFGG 208

  Fly   319 TTDLRHLAARRRNHRLLQRCSNEDALTLDLLSTGSHDRPDGASSKSSGTVVGSSDLTPSPSDSG- 382
            :.           |.:.|....:|:..:.|          .|.|.|.|   ||....|..:|.|
Mouse   209 SA-----------HNITQGIILQDSNMMSL----------KALSFSDG---GSKLAHPGKADKGA 249

  Fly   383 -------------ISELEAALKDRDSELSYLRQAMEHNEKVIFQVQKDKEVYWEHETQRLRLFYE 434
                         |.|||..|..|::.|..|:::.:..|....|.       :|...:|.|
Mouse   250 SCVRSPLSTDECTIQELEQKLLQRETALQKLQRSFDEKEFASGQT-------FEERPRRTR---- 303

  Fly   435 GQQREC----------QLKLRKMEQLLGLQQFQLKQHKLRQSEQVNRLQQQLDLARDSSQGLQQQ 489
             .:.||          ..|.::.:|:|.||..||:|.|.:..:::..|.::.||.....:..:::
Mouse   304 -DELECLEPKSKLKPPSQKSQRTQQVLQLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYERE 367

  Fly   490 VDALRHQLEDSEWRVCERNGEIALLKTQLKEAHLEINMKDHAIVSLKHSSNRSSSSSNSNSNKSC 554
            .......||:::|.||:::|||:|||.||||:.||:|.|...|:||
Mouse   368 KTNFAPALEETQWEVCQKSGEISLLKQQLKESQLEVNTKASEILSL------------------- 413

  Fly   555 DTNTSQSQPKQQAKEEQQQQQHPELQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLKQ 619
                     |.|.|:.:.:....||:.|..:...:.:..:.:..:.:.|:::.:.:
Mouse   414 ---------KAQLKDTRGKLDGMELKTQDLESALRTKGLELEVCENELQRKKNEAE--------- 460

  Fly   620 QHQPDQQQLQKIITLKDQVIGALTSELAKLRKELSDLAIAHEYGEEPCGRYTRLKQQLDNLNEIC 684
                          |..:.:..|..||.:||.:    |..|
Mouse   461 --------------LLREKVNLLEQELMELRAQ----AALH------------------------ 483

  Fly   685 QKTRKYTTTSASPTAVASPAAQVAPPAPSPAAHVATPSCAQELPKLDVLVQRLQLDQGQGTQQTL 749
                               .|.:.||                               |.|
Mouse   484 -------------------PAPLGPP-------------------------------GVG----- 493

  Fly   750 DTLIEESTTYAEDIAKLRQKLDDFRLNLELEKRQ---------------WSAEKDKVLGYQKQLQ 799
                   .|::|||..|:::||..|..|: |:||               |..||:||:.||:|||
Mouse   494 -------LTFSEDIPALQRELDRLRAELK-EERQGHDQMSSGFQHERLVWKEEKEKVIQYQRQLQ 550

  Fly   800 AHYIQMYQKLRCLDSA 815
            ..|:.|||:.:.|:.|
Mouse   551 QSYLAMYQRNQRLEKA 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15365	NP_001285030.1	Fez1	<735..812	CDD:462015	28/91 (31%)
Lzts1	NP_955396.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	135..190		10/54 (19%)
		Mplasa_alph_rch	<262..>473	CDD:275316	58/273 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	288..324		8/47 (17%)
		Fez1	378..568	CDD:462015	68/331 (21%)