DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgA and DGK4

DIOPT Version :9

Sequence 1:	NP_001259366.1	Gene:	rdgA / 31826	FlyBaseID:	FBgn0261549	Length:	1462	Species:	Drosophila melanogaster
Sequence 2:	NP_200577.2	Gene:	DGK4 / 835876	AraportID:	AT5G57690	Length:	487	Species:	Arabidopsis thaliana

Alignment Length:	401	Identity:	119/401 - (29%)
Similarity:	187/401 - (46%)	Gaps:	77/401 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   791 KEEKKEPRAFIVKPIP----SPEVIPVIVFINPKSGGNQGHKLLGKFQHLLNPRQVFDLTQGGPK 851
            |::..:..:.:..|:.    :||| |::||:||||||.||..:..:.|:|::..||:|||:..|.
plant    66 KDDSFDASSSVAPPLENNALTPEV-PLMVFVNPKSGGRQGPLIKERLQNLISEEQVYDLTEVKPN 129

  Fly   852 ------MG-LDMFRK---------APNLRVLACGGDGTVGWVLSVLDQIQPPLQ---PAPAVGVL 897
                  :| |:.|..         ...:|::..||||||||||..|.::.  ||   |.|.|.::
plant   130 EFIRYGLGCLEAFASRGDECAKEIREKMRIVVAGGDGTVGWVLGCLGELN--LQNRLPVPPVSIM 192

  Fly   898 PLGTGNDLARALGWGGSIFFQGYTDEPIGKILREIGMSQCVLMDRWRVKVT-PNDDVTDD----- 956
            ||||||||:|:.|||||..|.  ....|.:.|....::....:|.|.:.:| |:.::.|.
plant   193 PLGTGNDLSRSFGWGGSFPFA--WKSAIKRTLHRASVAPISRLDSWNILITMPSGEIVDPPYSLK 255

  Fly   957 -----HVDRS---KPNVPLN------VINNYFSFGVDAHIALEFHEAREAHPERFNSRLRNKMYY 1007
                 ::|::   :..:|.:      |..||||.|:||.:|..||..|...|...|..:.||:.|
plant   256 ATQECYIDQNLEIEGEIPPSTNGYEGVFYNYFSIGMDAQVAYGFHHLRNEKPYLANGPIANKIIY 320

  Fly  1008 GQMGG----------KDLILRQYRNLSQWVTLECDGQDFTGKLRDAGCHAVLFLNIPSYGGGTHP 1062
            ...|.          .|..||..:|:......:.|..::..........||:.||:.|||.|.:|
plant   321 SGYGCSQGWFLTHCINDPGLRGLKNIMTLHIKKLDSSEWEKVPVPKSVRAVVALNLHSYGSGRNP 385

  Fly  1063 WN-------DSFGASKPSIDDGLMEVVGL-----TTYQLPMLQAGMHGTCICQCRKARIITK--- 1112
            |.       :..|..:...||||:|:.||     .::.:..|.:..|   |.|....|:..:
plant   386 WGNLKQDYLEKRGFVEAQADDGLLEIFGLKQGWHASFVMVELISAKH---IAQAAAIRLEIRGGD 447

  Fly  1113 -RTIPMQVDGE 1122
             :...||:|||
plant   448 WKDAFMQMDGE 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgA	NP_001259366.1	C1_1	591..640	CDD:278556
		C1_1	661..725	CDD:278556
		LCB5	813..1140	CDD:224513	113/375 (30%)
		DAGKc	814..942	CDD:214487	55/146 (38%)
		DAGKa	969..1123	CDD:214486	51/180 (28%)
		ANK	1329..1447	CDD:238125
		ANK repeat	1329..1356	CDD:293786
		Ank_2	1330..1425	CDD:289560
		ANK repeat	1358..1391	CDD:293786
		ANK repeat	1393..1425	CDD:293786
		Ank_2	1399..>1459	CDD:289560
DGK4	NP_200577.2	DAGK_cat	90..230	CDD:395631	56/143 (39%)
DGK4	NP_200577.2	DAGK_acc	282..459	CDD:395484	51/180 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910