DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgA and DGK6

DIOPT Version :9

Sequence 1:	NP_001259366.1	Gene:	rdgA / 31826	FlyBaseID:	FBgn0261549	Length:	1462	Species:	Drosophila melanogaster
Sequence 2:	NP_194542.2	Gene:	DGK6 / 828928	AraportID:	AT4G28130	Length:	466	Species:	Arabidopsis thaliana

Alignment Length:	430	Identity:	122/430 - (28%)
Similarity:	198/430 - (46%)	Gaps:	93/430 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   799 AFIVKPIPSPEV---------IPVIVFINPKSGGNQGHKLLGKFQHLLNPRQVFDLTQGGP---- 850
            ::::.|...||.         .|::||||.||||..|.:|:..::.|||.:|||||....|
plant    25 SYVLSPEDEPEAQISCTTAPENPILVFINSKSGGQLGAELILTYRTLLNDKQVFDLEVETPDKVL 89

  Fly   851 -KMGLDMFRKAPN---------LRVLACGGDGTVGWVLSVLDQIQPPLQPAPAVGVLPLGTGNDL 905
             ::.|::.|...:         |:::..|||||.||:|.|:..:.  |...|.:..:||||||:|
plant    90 QRIYLNLERLKDDSLASKIRDKLKIIVAGGDGTAGWLLGVVSDLN--LSNPPPIATVPLGTGNNL 152

  Fly   906 ARALGWGGSIFFQGYTDEP-----IGKILREIGMSQCVLMDRWRVKVT---PND---DVTDDHVD 959
            ..|.|||..   ...||..     :||::....|.    :|.|::.:.   |.:   |:| ..:.
plant   153 PFAFGWGKK---NPGTDRSSVESFLGKVINAKEMK----IDNWKILMRMKHPKEGSCDIT-LKLP 209

  Fly   960 RSKPNV-PLNVIN------------NYFSFGVDAHIALEFHEAREAHPERFNSRLRNKMYYGQMG 1011
            .|.|.: |.:..|            ||||.|:||.::..||..|:.|||||.::|.|:..|.::.
plant   210 HSLPRIFPSDQENMEGYHTYRGGFWNYFSLGMDAQVSYAFHSQRKLHPERFKNQLVNQSTYLKLS 274

  Fly  1012 ------GKDLILRQYRNLSQWVTLE-CDGQDFTGKLRD----AGCHAVLFLNIPSYGGGTHPWND 1065
                  ...|.....:|:::...:: ||.   .|:..|    ....:::.||:||:.||.:||..
plant   275 CTQGWFFASLFHPSSQNIAKLAKIQICDR---NGQWNDLHIPQSIRSIVCLNLPSFSGGLNPWGT 336

  Fly  1066 -------SFGASKPSIDDGLMEVVGLTT--YQLPMLQAGMHGTCICQCRKARIITKRTIP----M 1117
                   ....:.|.:||||:|:||...  :.|.:|....|||.:.|..:.|:..|:...    |
plant   337 PNPKKQRDRSLTAPFVDDGLIEIVGFRNAWHGLILLSPNGHGTRLAQANRVRLEFKKGAAKHAYM 401

  Fly  1118 QVDGEACRVKPSVIEIELLNKALMLSKRKHGRGDVQVNPL 1157
            ::|||     |....:...::.:|:....||    |||.|
plant   402 RIDGE-----PWKQPLPSNDETVMVEISHHG----QVNML 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgA	NP_001259366.1	C1_1	591..640	CDD:278556
		C1_1	661..725	CDD:278556
		LCB5	813..1140	CDD:224513	111/388 (29%)
		DAGKc	814..942	CDD:214487	49/146 (34%)
		DAGKa	969..1123	CDD:214486	52/189 (28%)
		ANK	1329..1447	CDD:238125
		ANK repeat	1329..1356	CDD:293786
		Ank_2	1330..1425	CDD:289560
		ANK repeat	1358..1391	CDD:293786
		ANK repeat	1393..1425	CDD:293786
		Ank_2	1399..>1459	CDD:289560
DGK6	NP_194542.2	DAGK_cat	47..160	CDD:279163	44/114 (39%)
DGK6	NP_194542.2	DAGK_acc	235..407	CDD:295305	52/179 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910