Protein Alignment rdgA and Dgkk

DIOPT Version :9

• Sequence 1: NP_001259366.1
• Gene: rdgA / 31826
• FlyBaseID: FBgn0261549
• Length: 1462
• Species: Drosophila melanogaster
• Sequence 2: NP_808582.3
• Gene: Dgkk / 331374
• MGIID: 3580254
• Length: 1118
• Species: Mus musculus
• Alignment Length: 1066
• Identity: 246/1066 - (23%)
• Similarity: 365/1066 - (34%)
• Gaps: 399/1066 - (37%)

  Fly   532 TRSRSVDIVLPTDEQARYKALSMTGSTVTYADGRTASASNSRRPIRIVPDWTENA-VQGEHYW-- 593
            |..|.|.:|.||    |...........|...|.          ||.:|....|. :.|.|||
Mouse   124 TPHRKVSLVAPT----RQDMEEWINIIKTVQQGE----------IRQIPAAENNPFLVGMHYWYS 174

  Fly   594 --KPTSASGDLCCLNEECIKSGQRMKCSACQLVAHHNCIPFVNEKSTLACK---PTYRDVGIRQY 653
              .|.|...::|..|...: |...:.|..||:.:|..|....|:.    ||   .:..|..:...
Mouse   175 SSNPRSHFCNVCRENIPAL-SRDAVTCEVCQVKSHKFCALRANKD----CKWNTLSVTDDLLLPA 234

  Fly   654 REQTTTHHHWVHRKLEKG-KC----KQCGKFFPMKQAVQSKLFGSKEIVALACAWCHEIYHNKEA 713
            .|..|..|.||...:..| :|    |.||....::.              ..|.||....|.  |
Mouse   235 DEIQTMPHQWVEGNIPAGSQCVVCHKSCGSHHRLQD--------------FRCLWCGSTVHG--A 283

  Fly   714 CFNQAKIGEECRLGNYAPIIVPPSWIVKLPTKGNFKSSIRVSNKNNAASGSGGGGAGGGAGGGGG 778
            |  |.:..:||..|:....||||:                      |.|...|.|
Mouse   284 C--QKRFSKECSFGSRRSSIVPPT----------------------ALSDPRGDG---------- 314

  Fly   779 KSKKQTQRRQKGKEEKKEPRAFIVKP------IPSPEVIPVIVFINPKSGGNQGHKLLGKFQHLL 837
                                ..:|.|      .|.....|:::|||.|||.:||...|.||:..|
Mouse   315 --------------------QLVVSPDFWNLDWPLTCSCPLLIFINSKSGDHQGIIFLRKFKQYL 359

  Fly   838 NPRQVFDLTQGGPKMGLDMFRKAPNLRVLACGGDGTVGWVLSVLDQIQPPLQPAPAVGVLPLGTG 902
            ||.|||||.:|||:.|:.||:.....|||.|||||:|.||||.:|..  .|.....:.::|||||
Mouse   360 NPSQVFDLAKGGPEAGIAMFKNFARFRVLVCGGDGSVSWVLSTIDAY--GLHDRCQLAIIPLGTG 422

  Fly   903 NDLARALGWGGSIFFQGYTDEPIGKILREIGMSQCVLMDRWRVKV--TP---------------- 949
            |||||.||| |:::.:|  ..|: .||..:..:...::|||.|.:  ||
Mouse   423 NDLARVLGW-GAVWSKG--TSPL-DILSRVEQAHVRILDRWSVMIRETPRQAPLLKGQVAMDIPR 483

  Fly   950 ---------------------------------------NDDVTD-------------------- 955
                                                   .|.|.|
Mouse   484 FEAAAIKNVESATTELNKILKAKYPTEMVIATRFLCSAVEDFVEDIVKAWHQIKQNSTAVESVIL 548

  Fly   956 -----------------------------------------------DHVDRSK----------- 962
                                                           ||:.|:|
Mouse   549 KSDLMYDKLSVLIDLLAEDAVAASAERTATAYGSRSQADGKPFVPQLDHIARAKLELAERAQKLQ 613

  Fly   963 ----------------------------------------------------------------- 962
                                                                             
Mouse   614 QSLKLIIFQVEQVLDEESRQSLSVKNFTSSLFLGDGDDDDSDDYDQSPRHRSRCDILCSIPSLRN 678

  Fly   963 ---PNVPLN---------------VINNYFSFGVDAHIALEFHEAREAHPERFNSRLRNKMYYGQ 1009
               .|:.|.               |:||||..|:||.|:|||:..||.|||::||||:||::||.
Mouse   679 EDLDNLDLEHLHIAPETIRFKEKCVMNNYFGIGLDAKISLEFNSRREEHPEQYNSRLKNKIWYGL 743

  Fly  1010 MGGKDLILRQYRNLSQWVTLECDGQDFTGKLRDAGCHAVLFLNIPSYGGGTHPWNDSFGASK--- 1071
            :|.|:|:.|.||.|.:.:.|||||:    .:.......::.|||.||.||.:.|..:...::
Mouse   744 LGSKELLQRSYRKLEERIHLECDGE----AVSLPNLQGIVVLNITSYAGGVNFWGRNRATTEYDV 804

  Fly  1072 PSIDDGLMEVVGL-TTYQLPMLQ-AGMHGTCICQCRKARIIT---KRTIPMQVDGEACRVKPSVI 1131
            |:|:||.:|||.: .:.|:.|.: ..:....|.||.:. :||   :..:|:||||||...||.:|
Mouse   805 PAINDGKLEVVAIFGSVQMAMSRIVNLQQHRIAQCHEV-VITIDGEDGVPVQVDGEAWIQKPGLI 868

  Fly  1132 EIELLNKALMLSKRKHGRGDVQVNPLEKMQLHILR---VTMQQYEQYHYDKEM-----LRKLANK 1188
            :|:..|.|.||.:.:.....::....:..::..::   :..|:.:....|.|.     |.:||..
Mouse   869 KIKYKNVAQMLMRDRDFENSMKTWESKHTEIQAVQPPHLDFQESQDSLSDGEYAQMQHLARLAEN 933

  Fly  1189 LGQIEIESQCDL----EHV----------RNMLNTKFEESISYPKVSQDWCF-IDSCTAEHYFRI 1238
            |    |....||    :||          .|:||..|....|..:.....|. |::.:......:
Mouse   934 L----ISRLTDLSKVHQHVSVLMDSVNASANILNDVFYSQDSGNEAGAASCIPIETLSRTDAVDV 994

  Fly  1239 DRAQEHLHYICDIAIDELYILDHEAATMPQT------PDQERSFAA-------FSQRQAQNER-- 1288
            ..:.:.|:......:||..:.|.|...|.||      .:..|..|.       |.:.||.:.|
Mouse   995 TFSLKGLYDDTKAFLDENLLRDAEDRAMLQTALDAMNTELRRILAIGWLSQIFFPEEQASDTRSL 1059

  Fly  1289 ------------RQMDQAQGRGPGST 1302
                        ::..:.:|..|.|:
Mouse  1060 SRRFRIKFPKLGKKKQREEGEKPKSS 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdgA	NP_001259366.1	C1_1	591..640	CDD:278556	14/52 (27%)
		C1_1	661..725	CDD:278556	16/68 (24%)
		LCB5	813..1140	CDD:224513	144/552 (26%)
		DAGKc	814..942	CDD:214487	58/127 (46%)
		DAGKa	969..1123	CDD:214486	64/161 (40%)
		ANK	1329..1447	CDD:238125
		ANK repeat	1329..1356	CDD:293786
		Ank_2	1330..1425	CDD:289560
		ANK repeat	1358..1391	CDD:293786
		ANK repeat	1393..1425	CDD:293786
		Ank_2	1399..>1459	CDD:289560
Dgkk	NP_808582.3	PH	59..147	CDD:278594	7/26 (27%)
		PH_DGK_type2	60..154	CDD:270093	9/43 (21%)
		C1	170..219	CDD:237996	14/53 (26%)
		C1	242..292	CDD:237996	15/67 (22%)
		DAGKc	336..458	CDD:214487	58/127 (46%)
		DAGK_acc	703..860	CDD:295305	64/161 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846083
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840