DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32845 and ESS1

DIOPT Version :9

Sequence 1:	NP_728511.1	Gene:	CG32845 / 318243	FlyBaseID:	FBgn0052845	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_012551.2	Gene:	ESS1 / 853475	SGDID:	S000003778	Length:	170	Species:	Saccharomyces cerevisiae

Alignment Length:	168	Identity:	51/168 - (30%)
Similarity:	83/168 - (49%)	Gaps:	15/168 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LPFGWEERIAHSTKECYFYDTITRKVHFTLPPSHHREKDRNAWGAILGDYSDFNDQLRCRHILVK 137
            ||..|..|.:.|.|..||::..|:...:..|...::::       :.....|...::||.|||:|
Yeast    11 LPTPWTVRYSKSKKREYFFNPETKHSQWEEPEGTNKDQ-------LHKHLRDHPVRVRCLHILIK 68

  Fly   138 HSESDRCSSYRERMVRRTKQEALNKIMHARDLI-----QSGKFEFAELANMISDCCSARHGGDLG 197
            |.:|.|.:|:|...:..:||:|.:::   :.||     .|....|..||...|||.|.:.|||||
Yeast    69 HKDSRRPASHRSENITISKQDATDEL---KTLITRLDDDSKTNSFEALAKERSDCSSYKRGGDLG 130

  Fly   198 PLSLTQTPFVFERNILLLKDGELSEIFQTKAGYHILLR 235
            .....:....||.....||.||:|:|.::.:|.|::.|
Yeast   131 WFGRGEMQPSFEDAAFQLKVGEVSDIVESGSGVHVIKR 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32845	NP_728511.1	WW	73..103	CDD:278809	9/29 (31%)
CG32845	NP_728511.1	Rotamase_2	127..237	CDD:298667	40/114 (35%)
ESS1	NP_012551.2	WW	10..43	CDD:197736	10/31 (32%)
ESS1	NP_012551.2	Rotamase_2	59..170	CDD:421736	40/113 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346100
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0760
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S623
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001686
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10657
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.750