Protein Alignment CG10962 and DHRS11

DIOPT Version :9

• Sequence 1: NP_788887.1
• Gene: CG10962 / 31824
• FlyBaseID: FBgn0030073
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_077284.2
• Gene: DHRS11 / 79154
• HGNCID: 28639
• Length: 260
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 92/257 - (35%)
• Similarity: 147/257 - (57%)
• Gaps: 22/257 - (8%)

  Fly     1 MDRWQNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSLPAEQRMRFH-----Q 60
            |:||::|:|:::|||.|||||.||.||..||:|||.||....:|:    |.||.:...:     .
Human     6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEE----LAAECKSAGYPGTLIP 66

  Fly    61 HKCDVSQELQVDTAFEWIEKELGGIDVLINNAGIVLGGQLIDMPTKDINNILQTNLMGSIYCTKL 125
            ::||:|.|..:.:.|..|..:..|:|:.|||||:.....|:...|....::...|::....||:.
Human    67 YRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTRE 131

  Fly   126 AASSMRRRQV-AGHLIFVNSTAGVAGYKPDPADESLNAYTPSKFALTAVQEICRQELINQGSKIK 189
            |..||:.|.| .||:|.:||   ::|::..|...: :.|:.:|:|:||:.|..||||....:.|:
Human   132 AYQSMKERNVDDGHIININS---MSGHRVLPLSVT-HFYSATKYAVTALTEGLRQELREAQTHIR 192

  Fly   190 TTSINPGWVATEIV-------PDETKAKLGEV-ILQADDVAQAVLYALSTPPHTQVEQITLR 243
            .|.|:||.|.|:..       |::..|...:: .|:.:|||:||:|.||||.|.|:..|.:|
Human   193 ATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMR 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10962	NP_788887.1	YdfG	1..249	CDD:226674	92/257 (36%)
		NADB_Rossmann	1..243	CDD:304358	91/255 (36%)
DHRS11	NP_077284.2	Mgc4172-like_SDR_c	6..256	CDD:187601	92/257 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143370
Domainoid	1	1.000	154	1.000	Domainoid score	I4257
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41560
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3916
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D1190834at2759
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		otm40752
orthoMCL	1	0.900	-	-		OOG6_100320
Panther	1	1.100	-	-	O	PTHR43115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X367
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.810