Protein Alignment CG10962 and HSD17B11

DIOPT Version :9

• Sequence 1: NP_788887.1
• Gene: CG10962 / 31824
• FlyBaseID: FBgn0030073
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_057329.3
• Gene: HSD17B11 / 51170
• HGNCID: 22960
• Length: 300
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 57/232 - (24%)
• Similarity: 99/232 - (42%)
• Gaps: 25/232 - (10%)

  Fly     8 VAVISGASSGIG-------AACARLLVAAGLQVVGLARRTDRLEQLRQSLPAEQRMRFHQHKCDV 65
            :.:|:||..|||       |.....||...:...||.....:.:.|        ..:.|....|.
Human    38 IVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL--------GAKVHTFVVDC 94

  Fly    66 SQELQVDTAFEWIEKELGGIDVLINNAGIVLGGQLIDMPTKDINNILQTNLMGSIYCTKLAASSM 130
            |....:.::.:.::.|:|.:.:|:||||:|....|.......|....:.|::...:.||....:|
Human    95 SNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAM 159

  Fly   131 RRRQVAGHLIFVNSTAGVAGYKPDPADESLNAYTPSKFALTAVQEICRQELIN-QGSKIKTTSIN 194
            .:.. .||::.|   |..||:...|   .|.||..||||.....:....||.. |.:.:|||.:.
Human   160 TKNN-HGHIVTV---ASAAGHVSVP---FLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLC 217

  Fly   195 PGWVATEIVPDETKAKLGEVILQADDVAQAVLYALST 231
            |.:|.|..:.:.: ..||.. |:.::|...:::.:.|
Human   218 PNFVNTGFIKNPS-TSLGPT-LEPEEVVNRLMHGILT 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10962	NP_788887.1	YdfG	1..249	CDD:226674	57/232 (25%)
		NADB_Rossmann	1..243	CDD:304358	57/232 (25%)
HSD17B11	NP_057329.3	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	57/232 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910