DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10962 and CG8757

DIOPT Version :9

Sequence 1:	NP_788887.1	Gene:	CG10962 / 31824	FlyBaseID:	FBgn0030073	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_648664.2	Gene:	CG8757 / 39528	FlyBaseID:	FBgn0036380	Length:	252	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	122/257 - (47%)
Similarity:	177/257 - (68%)	Gaps:	13/257 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDRWQNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSLPAEQRMRFHQHKCDV 65
            |:||.|:|||:||||:||||||.|.|:.||:.|||||||.:|:|:||..|..||:.|.|..|||:
  Fly     1 MERWCNKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHAIKCDI 65

  Fly    66 SQELQVDTAFEWIEKELGGIDVLINNAGIVLGGQLI---DMPTKDINNILQTNLMGSIYCTKLAA 127
            :||.||..||:|..::|||:|||::||||:..|:|.   |.|.  :.:.::||:||::||.:.:.
  Fly    66 TQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPA--MRSTIETNIMGTVYCVRESF 128

  Fly   128 SSMRRRQVAGHLIFVNSTAGVAGYK-PD--PADESLNAYTPSKFALTAVQEICRQELINQGSKIK 189
            .||:||...||::.|||   ||||: |:  |...|||.|..:||||.|:.||.|||.....:.::
  Fly   129 RSMKRRGTEGHVVIVNS---VAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKTAVR 190

  Fly   190 TTSINPGWVATEIVPDETKA--KLGEVILQADDVAQAVLYALSTPPHTQVEQITLRAVGEYF 249
            .::::||.|.|.|:|::.:.  |....:|::||||.|||:|:.|||:.||..||::..||.|
  Fly   191 VSTVSPGIVDTVILPEQIQGIIKQHMPMLRSDDVADAVLWAIGTPPNVQVHNITIKPQGEKF 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10962	NP_788887.1	YdfG	1..249	CDD:226674	121/255 (47%)
CG10962	NP_788887.1	NADB_Rossmann	1..243	CDD:304358	119/249 (48%)
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	121/255 (47%)
CG8757	NP_648664.2	NADB_Rossmann	1..247	CDD:304358	119/250 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442637
Domainoid	1	1.000	86	1.000	Domainoid score	I2775
eggNOG	1	0.900	-	-		E2759_KOG1205
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I2312
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D101130at6960
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		mtm6354
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X367
	11	10.910