Protein Alignment CG10962 and HSD11B1L

DIOPT Version :9

• Sequence 1: NP_788887.1
• Gene: CG10962 / 31824
• FlyBaseID: FBgn0030073
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_001254797.1
• Gene: HSD11B1L / 374875
• HGNCID: 30419
• Length: 333
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 57/254 - (22%)
• Similarity: 95/254 - (37%)
• Gaps: 37/254 - (14%)

  Fly     5 QNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSLPAEQRM----RFHQHKCDV 65
            |....:::||::|:|...|......|..:|    .|...|.|.|.:....|.    :......|:
Human    75 QGARVLLTGANAGVGEELAYHYARLGSHLV----LTAHTEALLQKVVGNCRKLGAPKVFYIAADM 135

  Fly    66 SQELQVDTAFEWIEKELGGIDVLI-NNAGIVLGGQLIDMPTKDINNILQTNLMGSIYCTKLAASS 129
            :.....::..::...:|||:|.|: |:.|....|.....| :....::|.|.:..:..|..|..|
Human   136 ASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSP-QATRWLMQVNFVSYVQLTSRALPS 199

  Fly   130 MRRRQVAGHLIFVNSTAGVAGYKPDPADESLNAYTPSKFALTAVQEICRQELINQGSKIKTT--- 191
            :...:  |.|:.|:|..|..     |...| ..|:.:||||.......|:||..|...:..|
Human   200 LTDSK--GSLVVVSSLLGRV-----PTSFS-TPYSAAKFALDGFFGSLRRELDVQDVNVAITMCV 256

  Fly   192 -SINPGWVATEIVPDETKAKLGEVILQADDVAQAVLYALSTPPHTQVEQITLRAVGEYF 249
             .:.....|.|.|...|:.|..    .....|.||:...:|           ||.|.::
Human   257 LGLRDRASAAEAVRGVTRVKAA----PGPKAALAVIRGGAT-----------RAAGVFY 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10962	NP_788887.1	YdfG	1..249	CDD:226674	57/252 (23%)
		NADB_Rossmann	1..243	CDD:304358	54/246 (22%)
HSD11B1L	NP_001254797.1	GVQW	3..>26	CDD:290611
		NADB_Rossmann	74..302	CDD:304358	57/254 (22%)
		PRK08251	78..302	CDD:181324	56/251 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900