DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10962 and CG40486

DIOPT Version :9

Sequence 1:	NP_788887.1	Gene:	CG10962 / 31824	FlyBaseID:	FBgn0030073	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001036311.2	Gene:	CG40486 / 3355162	FlyBaseID:	FBgn0263830	Length:	247	Species:	Drosophila melanogaster

Alignment Length:	252	Identity:	118/252 - (46%)
Similarity:	166/252 - (65%)	Gaps:	8/252 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDRWQNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSLPAEQRMRFHQHKCDV 65
            |:||.:||||::|||||||||.||.||:||:.|||||||.||::.:::.||.|.:.|.|...|||
  Fly     1 MERWHDRVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKEQLPPELQGRLHAIHCDV 65

  Fly    66 SQELQVDTAFEWIEKELGGIDVLINNAGIVLGGQLIDMPTKDINNILQTNLMGSIYCTKLAASSM 130
            .....|..||:|||::|||.|:|:||||.:..|||:.:..:.:..:|..||||.:.||:.|..||
  Fly    66 EDLDSVTAAFDWIEEQLGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVVICTRRAFRSM 130

  Fly   131 RRRQVAGHLIFVNSTAGVAGYKPDPADE--SLNAYTPSKFALTAVQEICRQELINQGSKIKTTSI 193
            ::|:|.||:|.:||..|.....| |.||  .||.|..:|..:||:.|:.||||....:|||.|||
  Fly   131 QQREVDGHVILINSLTGRNIINP-PGDELQVLNMYPLTKHGVTAMLEVLRQELRGFKTKIKVTSI 194

  Fly   194 NPGWVATEIVPDETKAKLGEV-ILQADDVAQAVLYALSTPPHTQVEQITLRAVGEYF 249
            .||...|||:|    :..|.: :|:.||:|..::|.|.||.|.||.::|::.:||.|
  Fly   195 TPGVTDTEILP----SGYGILPMLKPDDIAAGIMYVLGTPAHVQVHELTIKPLGEPF 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10962	NP_788887.1	YdfG	1..249	CDD:226674	117/250 (47%)
CG10962	NP_788887.1	NADB_Rossmann	1..243	CDD:304358	115/244 (47%)
CG40486	NP_001036311.2	YdfG	1..247	CDD:226674	117/250 (47%)
CG40486	NP_001036311.2	NADB_Rossmann	1..242	CDD:304358	115/245 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442630
Domainoid	1	1.000	86	1.000	Domainoid score	I2775
eggNOG	1	0.900	-	-		E2759_KOG1205
Homologene	1	1.000	-	-		H41560
Inparanoid	1	1.050	87	1.000	Inparanoid score	I2312
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D101130at6960
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		mtm6354
orthoMCL	1	0.900	-	-		OOG6_100320
Panther	1	1.100	-	-	P	PTHR43115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X367
	13	12.810