Protein Alignment CG10962 and DHRS7C

DIOPT Version :9

• Sequence 1: NP_788887.1
• Gene: CG10962 / 31824
• FlyBaseID: FBgn0030073
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_001207422.1
• Gene: DHRS7C / 201140
• HGNCID: 32423
• Length: 312
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 65/260 - (25%)
• Similarity: 104/260 - (40%)
• Gaps: 47/260 - (18%)

  Fly     5 QNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSL-----PAEQRMRFHQHKCD 64
            ||:|.||:.|.||:|..|||:....|.::|...:..:|||.|..:|     |::|.........|
Human    36 QNKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPSKQTFTPKLVLLD 100

  Fly    65 VSQELQV-DTAFEWIEKELGGIDVLINNAGIVLGGQLIDMPTKDINNILQTNLMGSIYCTKLAAS 128
            :|....| |.|.|.::. .|.:|:|||||.:.:.|....:..:....|:..|..|.|..||....
Human   101 LSDISCVPDVAKEVLDC-YGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKALLP 164

  Fly   129 SMRRRQVAGHLIFVNSTAGVAGYKPDPADESLNAYTPSKFALTAVQEICRQELINQGSKIKTTS- 192
            :|..|: .|.::.||:..|..|.      .....|..||.|.....:..|.|:......|.|.|
Human   165 NMISRR-TGQIVLVNNIQGKFGI------PFRTTYAASKHAALGFFDCLRAEVEEYDVVISTVSP 222

  Fly   193 ------------------------------INPGWVATEIVPDETKAKLGEVILQADDVAQAVLY 227
                                          ::|..||.|::  .|..:..:.:..|:.:.:|.:|
Human   223 TFIRSYHVYPEQGNWEASIWKFFFRKLTYGVHPVEVAEEVM--RTVRRKKQEVFMANPIPKAAVY 285

  Fly   228  227
            Human   286  285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10962	NP_788887.1	YdfG	1..249	CDD:226674	65/260 (25%)
		NADB_Rossmann	1..243	CDD:304358	65/260 (25%)
DHRS7C	NP_001207422.1	11beta-HSD1_like_SDR_c	35..297	CDD:187593	65/260 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810