DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10962 and dhrs7c

DIOPT Version :9

Sequence 1:	NP_788887.1	Gene:	CG10962 / 31824	FlyBaseID:	FBgn0030073	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	XP_012826975.2	Gene:	dhrs7c / 100135266	XenbaseID:	XB-GENE-5956201	Length:	704	Species:	Xenopus tropicalis

Alignment Length:	198	Identity:	54/198 - (27%)
Similarity:	95/198 - (47%)	Gaps:	13/198 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSL--PAEQRMRFHQH--KCDV 65
            :|:|.||:.|.||:|..|:|:..:||.::|...:..::||.|..:|  .|:..:.|...  ..|:
Frog    36 KNKVVVITDAISGLGKECSRVFHSAGARLVLCGKTWEKLEALHDALISVADPSVTFTPKLVLLDI 100

  Fly    66 SQELQVDTAFEWIEKELGGIDVLINNAGIVLGGQLIDMPTKDINNILQTNLMGSIYCTKLAASSM 130
            |....::...:.|:...|.:|||||||.:.:.|.|..:..:....|:..|..|.|...|.....|
Frog   101 SDINNMEAMGKEIQDCYGCVDVLINNASMKMKGPLQSVSLELDKKIMDANYFGPITLVKAILPHM 165

  Fly   131 RRRQVAGHLIFVNSTAGVAGYKPDPADESLNAYTPSKFALTAVQEICRQELINQGSKIKTTSINP 195
            ..|: .|.::.||:..|..|. |..|     ||..||.|:....:..|.|:  :...:..::::|
Frog   166 ISRR-TGQIVLVNTIQGKIGV-PFRA-----AYAASKHAIQGFFDCLRAEV--EEFDVSVSTVSP 221

  Fly   196 GWV 198
            .::
Frog   222 TFI 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10962	NP_788887.1	YdfG	1..249	CDD:226674	54/198 (27%)
CG10962	NP_788887.1	NADB_Rossmann	1..243	CDD:304358	54/198 (27%)
dhrs7c	XP_012826975.2	11beta-HSD1_like_SDR_c	35..257	CDD:187593	54/198 (27%)
dhrs7c	XP_012826975.2	LAP2alpha	425..629	CDD:371604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910