DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32820 and Tekt4

DIOPT Version :9

Sequence 1:	NP_728441.1	Gene:	CG32820 / 318228	FlyBaseID:	FBgn0052820	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_082227.1	Gene:	Tekt4 / 71840	MGIID:	1919090	Length:	447	Species:	Mus musculus

Alignment Length:	460	Identity:	152/460 - (33%)
Similarity:	242/460 - (52%)	Gaps:	35/460 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 TKHPWRPAMAYELIQVKHMPEQPVTNQLTKQCFLPKGMKTDGMIFPNLVTGFDRNPQHAARAALY 204
            ||.|     |.:.|.|..:|.:..........:...|:.|.|.                 |.|.|
Mouse     9 TKEP-----APQSIDVCELPRKEYEVACNTGAYTSSGLATAGF-----------------RTAKY 51

  Fly   205 TRYTSNEWYNNNMTKYSESNMNRNLSERMRNDAVRLMRETDEKATSGQRDAGRRLGERITDLTFW 269
            .|   :||:.|:..:|.::..:|:.|||.|:::.:|:.||...|...|.|:.|::|||:.|:..|
Mouse    52 LR---DEWFQNSYARYHQAFADRDYSERQRHESGQLVAETGALAQRTQLDSTRKVGERLEDMHCW 113

  Fly   270 RNELNAELEKLIAEMSDINELQR-QCGKALLDLEIPLHIAQECLFHRESRQGTEKVHDIVEKALL 333
            ::||..|:::|.:| :|:...|: :..:||....:|..||.:.|..||.||..:.|.|.||..||
Mouse   114 KSELQREIDELSSE-TDLMMAQKLRLQRALDATSVPYSIATDNLQCRERRQHPDLVRDYVEVELL 177

  Fly   334 VEINNLRNSRDRLGGLHEKISKQALD----CRGAQHLLEDDVSHKESSLGIDSMCHQLNNHSRGI 394
            .|...:||.::.|    ::...||:|    .|..:...|.:.|.|.....||..|.:..|.|..:
Mouse   178 KETELIRNIQELL----KRTIGQAVDQIRLNREHKESCEMNWSDKVEVYNIDDTCSRYTNESTQV 238

  Fly   395 TYYGGIEKFDPSVSTQESWAQASSEHVRRSQAERAKLSQLRSDAQSVVNSVATTVWDFWSNTNNA 459
            .:|....||:.|.||.|:||:.:.:::.|::.||.....||.....::...|..:.......|:|
Mouse   239 QFYPHSSKFEESASTPETWAKFNHDNLLRAERERLASVNLRKLIDCILRDTAEDLRLQCDAVNSA 303

  Fly   460 FDRRSQEMAEAKNRVQLHLQKVQQELFDMEKHLFLLQKAIQDKSGPLKVAQTRLEARSHREGVEL 524
            |..|.||:.::..::|.||:|...|:.|.|..:..|::||:||..||:||||||..||||..|||
Mouse   304 FSSRCQELDDSLQKLQYHLRKTLTEITDQEHQIAALKQAIKDKEAPLRVAQTRLYQRSHRPNVEL 368

  Fly   525 CKDHAQDRLVQEVQDIQGAVETLHHKLMEAEATHQGLLKTRCTLEVDLRNKVNALFIDREKCMSL 589
            |:|:||.||:.||:::..::..|..||.:||...:.|..:|.:||.|:..|.|:|||||:|||:.
Mouse   369 CRDNAQFRLLSEVEELNMSLRALKEKLQDAEQALRNLEDSRMSLEKDIAVKTNSLFIDRQKCMTH 433

  Fly   590 RRSFP 594
            |..:|
Mouse   434 RNRYP 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32820	NP_728441.1	Tektin	212..591	CDD:281184	135/383 (35%)
Tekt4	NP_082227.1	Tektin	56..434	CDD:308655	135/382 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2685
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59762
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000711
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3872
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850