DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32820 and tekt3

DIOPT Version :9

Sequence 1:	NP_728441.1	Gene:	CG32820 / 318228	FlyBaseID:	FBgn0052820	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_701169.2	Gene:	tekt3 / 572368	ZFINID:	ZDB-GENE-080130-2	Length:	488	Species:	Danio rerio

Alignment Length:	473	Identity:	183/473 - (38%)
Similarity:	288/473 - (60%)	Gaps:	15/473 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 AAYETPTKHPWRPAMAYELIQVK-HMPEQPVT-NQLTKQCFLPKGMKTDGMIFPNLVTGFDRNPQ 196
            |.|..|....:.||::......: |.|  |:: ||.:...:........|...|.| :...|:..
Zfish    10 ATYTRPKTSHFLPAISTTASSYRSHQP--PLSLNQNSNMPWRTNSYYRSGSAIPTL-SALQRDNL 71

  Fly   197 HAARA----------ALYTRYTSNEWYNNNMTKYSESNMNRNLSERMRNDAVRLMRETDEKATSG 251
            ...||          ||.|||...:||.:|.:.|.||..:||.:||:|.|.:||:::.::.....
Zfish    72 ELVRAKTMFYPSNRTALSTRYMPEDWYKSNQSNYRESESSRNSAERLRRDTIRLIQDKEQLTRRT 136

  Fly   252 QRDAGRRLGERITDLTFWRNELNAELEKLIAEMSDINELQRQCGKALLDLEIPLHIAQECLFHRE 316
            |....:.:|||:.|::|||:|:|.|::.::.|:|.:::::|:..:||.:.|.||.:|||||||||
Zfish   137 QDTTSKNIGERLNDISFWRSEINHEIDNMVTEISALSDVKRRLERALAETEGPLQVAQECLFHRE 201

  Fly   317 SRQGTEKVHDIVEKALLVEINNLRNSRDRLGGLHEKISKQALDCRGAQHLLEDDVSHKESSLGID 381
            .|...:.|||.||..|:.|::.:::.::|:....|:...|....|.|||.||.|:|.|.::..||
Zfish   202 KRMSIDLVHDDVEIDLIKEVDVIKSCQERMRRHLERAVAQLAANRAAQHELERDLSDKVTAQRID 266

  Fly   382 SMCHQLNNHSRGITYYGGIEKFDPSVSTQESWAQASSEHVRRSQAERAKLSQLRSDAQSVVNSVA 446
            ..||.|.|.|.||:||.||::.|||:|..:||::.:.:::..||:|||...:||.:.:.::|:.:
Zfish   267 DRCHHLRNTSDGISYYRGIDRLDPSISLPDSWSKFTDDNILHSQSERAASHKLRDEIEILLNATS 331

  Fly   447 TTVWDFWSNTNNAFDRRSQEMAEAKNRVQLHLQKVQQELFDMEKHLFLLQKAIQDKSGPLKVAQT 511
            ..:|:.:::.|.:|..|..|.|:.||.:|.||.|..||::..|..:..|:|||:||..|||||||
Zfish   332 NEMWNQFNSVNVSFTNRISETADTKNNLQTHLAKTLQEIYQTEMLIEALKKAIRDKENPLKVAQT 396

  Fly   512 RLEARSHREGVELCKDHAQDRLVQEVQDIQGAVETLHHKLMEAEATHQGLLKTRCTLEVDLRNKV 576
            |||.|:.|..||||:|:...||:.||::|:..:..|..:|||||.|.|.|:||:.|||.||..|.
Zfish   397 RLEERTRRPNVELCRDNPHHRLITEVREIEDTIHKLRDRLMEAENTLQTLVKTKITLEHDLSIKA 461

  Fly   577 NALFIDREKCMSLRRSFP 594
            |:||:|:|||||:|:|||
Zfish   462 NSLFLDQEKCMSMRKSFP 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32820	NP_728441.1	Tektin	212..591	CDD:281184	158/378 (42%)
tekt3	XP_701169.2	Tektin	97..476	CDD:281184	158/378 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594859
Domainoid	1	1.000	339	1.000	Domainoid score	I1071
eggNOG	1	0.900	-	-		E1_KOG2685
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12896
Inparanoid	1	1.050	349	1.000	Inparanoid score	I2264
OMA	1	1.010	-	-		QHG59762
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000711
OrthoInspector	1	1.000	-	-		oto40665
orthoMCL	1	0.900	-	-		OOG6_108589
Panther	1	1.100	-	-	LDO	PTHR19960
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3872
SonicParanoid	1	1.000	-	-		X3619
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.830