DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32820 and Tekt3

DIOPT Version :9

Sequence 1:	NP_728441.1	Gene:	CG32820 / 318228	FlyBaseID:	FBgn0052820	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001019910.1	Gene:	Tekt3 / 287392	RGDID:	1310582	Length:	490	Species:	Rattus norvegicus

Alignment Length:	501	Identity:	183/501 - (36%)
Similarity:	286/501 - (57%)	Gaps:	50/501 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 NEYNERKDHRNLMESYPWSQAGAPPCMEPVMGPSIPPRVGAAYETPTKHPWRPAMAYELIQVKHM 158
            :.|..|..||||..|.                 |:|.|....|:|...:   |.:|
  Rat    31 SSYRNRFPHRNLTHSL-----------------SLPWRPSTYYKTAYNY---PTLA--------- 66

  Fly   159 PEQPVTNQLTKQCFLPKGMKTDGMIFPNLVTGFDRNPQHAARAALYTRYTSNEWYNNNMTKYSES 223
            |....:..:.:...||                |..|     |..|:||||.::||.:.:..:.||
  Rat    67 PLSSTSQSVCESTMLP----------------FVSN-----RTTLFTRYTPDDWYRSTLVGFQES 110

  Fly   224 NMNRNLSERMRNDAVRLMRETDEKATSGQRDAGRRLGERITDLTFWRNELNAELEKLIAEMSDIN 288
            |.:|:.|||:|.|..||:::..::....|.|:.:.||||:.|:.||::|:..||:::|.|.:.:.
  Rat   111 NCSRHNSERLRVDTSRLIQDKYQQIRKTQADSTQNLGERVNDIAFWKSEIIHELDEMIGETNALT 175

  Fly   289 ELQRQCGKALLDLEIPLHIAQECLFHRESRQGTEKVHDIVEKALLVEINNLRNSRDRLGGLHEKI 353
            :::|:..:.|::.:.||.:|:|||||||.|.|.:.|||..||.||.|:..:...::|:....:|.
  Rat   176 DIKRRLERGLIETDAPLQVARECLFHREKRMGIDLVHDEAEKELLTEVETVLCCQERMRRHLDKA 240

  Fly   354 SKQALDCRGAQHLLEDDVSHKESSLGIDSMCHQLNNHSRGITYYGGIEKFDPSVSTQESWAQASS 418
            ..|....|.|||.||.|:|.|:::|.||..|..|.|.|:|::|:.|:|..|.:||..||||:.:.
  Rat   241 IAQLASDRSAQHELEKDLSDKQAALRIDDKCKHLRNTSQGVSYFRGVENVDATVSVPESWAKFTD 305

  Fly   419 EHVRRSQAERAKLSQLRSDAQSVVNSVATTVWDFWSNTNNAFDRRSQEMAEAKNRVQLHLQKVQQ 483
            ::|.|||:|||..::||.|.::::..:|..:|:.::..|.||..|..|..:|||::.:||.|..|
  Rat   306 DNVLRSQSERAASAKLREDTENLLIVIANEMWNQFNKVNVAFTNRIAETVDAKNKIHIHLSKTLQ 370

  Fly   484 ELFDMEKHLFLLQKAIQDKSGPLKVAQTRLEARSHREGVELCKDHAQDRLVQEVQDIQGAVETLH 548
            |:|..|..:..::|||::||..||||||||:.|:.|..:|||:|.||.|||.||.::...::||.
  Rat   371 EIFQTEMAIESIRKAIKEKSAFLKVAQTRLDERTRRPNIELCRDIAQLRLVNEVYEVDETIQTLQ 435

  Fly   549 HKLMEAEATHQGLLKTRCTLEVDLRNKVNALFIDREKCMSLRRSFP 594
            .:|.::|.|.|.|..|:.|||.||..|.|.|:||:|||||:|.|:|
  Rat   436 QRLRDSEDTLQSLAHTKATLEHDLAVKANTLYIDQEKCMSMRNSYP 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32820	NP_728441.1	Tektin	212..591	CDD:281184	155/378 (41%)
Tekt3	NP_001019910.1	Tektin	99..477	CDD:281184	155/377 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352895
Domainoid	1	1.000	324	1.000	Domainoid score	I1168
eggNOG	1	0.900	-	-		E1_KOG2685
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12896
Inparanoid	1	1.050	338	1.000	Inparanoid score	I2304
OMA	1	1.010	-	-		QHG59762
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000711
OrthoInspector	1	1.000	-	-		otm45222
orthoMCL	1	0.900	-	-		OOG6_108589
Panther	1	1.100	-	-	LDO	PTHR19960
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3619
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760