DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32808 and PRSS1

DIOPT Version :9

Sequence 1:	NP_726740.1	Gene:	CG32808 / 318221	FlyBaseID:	FBgn0052808	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	255	Identity:	85/255 - (33%)
Similarity:	122/255 - (47%)	Gaps:	13/255 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LALFYTATFLLAGASGEDGKIVNGTTAGPGEFPFVVSLRRAKSGRHSCGATLLNPYWVLTAAHCV 74
            |.|.:.|. .||....:|.|||.|........|:.|||   .||.|.||.:|:|..||::|.||.
Human   230 LILTFVAA-ALAAPFDDDDKIVGGYNCEENSVPYQVSL---NSGYHFCGGSLINEQWVVSAGHCY 290

  Fly    75 RGSSPEQLDLQYGSQMLARNSSQVARVAAIFVHPGYEPEDKYVNDIALLQLAQSVALSKFVQPVR 139
            :.....:|. ::..::|..| .|....|.|..||.|: .....|||.|::|:....::..|..:.
Human   291 KSRIQVRLG-EHNIEVLEGN-EQFINAAKIIRHPQYD-RKTLNNDIMLIKLSSRAVINARVSTIS 352

  Fly   140 LPEPRQVTPGNASAVLAGWGLNATGGV-VQQHLQKVKLQVFSDTECSERHQTYLHDSQICAGLPE 203
            ||.....|  ....:::|||..|:.|. ....||.:...|.|..:|...:...:..:..|.|..|
Human   353 LPTAPPAT--GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLE 415

  Fly   204 GGKGQCSGDSGGPLLLIGSDTQVGIVSWSIKPCARPPFPGVFTEVSAYVDWIVETVNSYS 263
            |||..|.||||||::..|.  ..|:|||. ..||:...|||:|:|..||.||..|:.:.|
Human   416 GGKDSCQGDSGGPVVCNGQ--LQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAANS 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32808	NP_726740.1	Tryp_SPc	29..255	CDD:214473	75/226 (33%)
CG32808	NP_726740.1	Tryp_SPc	30..258	CDD:238113	76/228 (33%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	75/226 (33%)
		Tryp_SPc	249..467	CDD:238113	76/228 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8476
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920