DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32808 and PROC

DIOPT Version :9

Sequence 1:	NP_726740.1	Gene:	CG32808 / 318221	FlyBaseID:	FBgn0052808	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_024308770.1	Gene:	PROC / 5624	HGNCID:	9451	Length:	576	Species:	Homo sapiens

Alignment Length:	256	Identity:	83/256 - (32%)
Similarity:	131/256 - (51%)	Gaps:	18/256 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DGKIVNGTTAGPGEFPFVVSLRRAKSGRHSCGATLLNPYWVLTAAHCVRGSSPEQLDLQYGSQML 91
            |.::::|.....|:.|:.|.|..:|. :.:|||.|::|.||||||||:..|  ::|.::.|...|
Human   324 DPRLIDGKMTRRGDSPWQVVLLDSKK-KLACGAVLIHPSWVLTAAHCMDES--KKLLVRLGEYDL 385

  Fly    92 AR--NSSQVARVAAIFVHPGYEPEDKYVNDIALLQLAQSVALSKFVQPVRLPE----PRQVTPGN 150
            .|  .......:..:||||.|. :....||||||.|||...||:.:.|:.||:    .|::....
Human   386 RRWEKWELDLDIKEVFVHPNYS-KSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAG 449

  Fly   151 ASAVLAGWGLNATGGVVQQH-----LQKVKLQVFSDTECSERHQTYLHDSQICAGLPEGGKGQCS 210
            ...::.|||.:::.....:.     |..:|:.|....||||.....:.::.:|||:....:..|.
Human   450 QETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACE 514

  Fly   211 GDSGGPLL--LIGSDTQVGIVSWSIKPCARPPFPGVFTEVSAYVDWIVETVNSYSPPSSLW 269
            ||||||::  ..|:...||:|||. :.|......||:|:||.|:|||...:.....|...|
Human   515 GDSGGPMVASFHGTWFLVGLVSWG-EGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSW 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32808	NP_726740.1	Tryp_SPc	29..255	CDD:214473	78/238 (33%)
CG32808	NP_726740.1	Tryp_SPc	30..258	CDD:238113	80/240 (33%)
PROC	XP_024308770.1	GLA	117..168	CDD:214503
		EGF_CA	182..213	CDD:238011
		FXa_inhibition	255..290	CDD:317114
		Tryp_SPc	328..563	CDD:238113	80/239 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910