DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32808 and Prss53

DIOPT Version :9

Sequence 1:	NP_726740.1	Gene:	CG32808 / 318221	FlyBaseID:	FBgn0052808	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	315	Identity:	87/315 - (27%)
Similarity:	133/315 - (42%)	Gaps:	75/315 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 AWLARLALFYTATFLLAG------ASGEDG----KIVNGTTAGPGEFPFVVSLRRAKSGRHSCGA 59
            :|...| |...|..::.|      |.|:.|    :...|.|. |||:|:..|:||  .|.|.|..
  Rat     4 SWGPEL-LIVGAVIVIEGLQAAQRACGQRGPGPPEPQEGNTL-PGEWPWQASVRR--QGVHICSG 64

  Fly    60 TLLNPYWVLTAAHCVRGSSPEQL---DLQYGS---QMLARNSSQVARVAAIFVHPGYEPEDKYVN 118
            :|:...||||||||....:..:|   .:..||   :.|:..:.:|. |||:.:...|....: .:
  Rat    65 SLVADTWVLTAAHCFEKMATAELSSWSVVLGSLKQEGLSPGAEEVG-VAALQLPKAYNHYSQ-GS 127

  Fly   119 DIALLQLAQSVALSKFVQPVRLPEPRQVTPGNASAVLAGWGLNA---------------TGGV-- 166
            |:|||||...:..:...    ||:|....|..||....||..|.               ||.|
  Rat   128 DLALLQLTHPIVHTTLC----LPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRESQTGSVLT 188

  Fly   167 --------------------VQQHLQKVKLQVFSDTEC----SERHQTYL----HDSQICAGLPE 203
                                |.:.|:.::|::.|...|    :..||..|    ....:|.|...
  Rat   189 VLALCSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTCNCLYNRLHQRLLANPARSGMLCGGAQP 253

  Fly   204 GGKGQCSGDSGGPLLLIGSD---TQVGIVSWSIKPCARPPFPGVFTEVSAYVDWI 255
            |.:|.|.||||||::....|   .||||:|:: ..||:...|.:.|:::|:..|:
  Rat   254 GVQGPCQGDSGGPVMCREPDGHWVQVGIISFT-SNCAQEDTPVLLTDMAAHSSWL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32808	NP_726740.1	Tryp_SPc	29..255	CDD:214473	78/279 (28%)
CG32808	NP_726740.1	Tryp_SPc	30..258	CDD:238113	79/280 (28%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	77/272 (28%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100