DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32808 and HPN

DIOPT Version :10

Sequence 1:NP_726740.1 Gene:CG32808 / 318221 FlyBaseID:FBgn0052808 Length:284 Species:Drosophila melanogaster
Sequence 2:NP_002142.1 Gene:HPN / 3249 HGNCID:5155 Length:417 Species:Homo sapiens


Alignment Length:275 Identity:90/275 - (32%)
Similarity:128/275 - (46%) Gaps:49/275 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 KIVNGTTAGPGEFPFVVSLRRAKSGRHSCGATLLNPYWVLTAAHC-----------------VRG 76
            :||.|.....|.:|:.||||  ..|.|.||.:||:..||||||||                 |..
Human   162 RIVGGRDTSLGRWPWQVSLR--YDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQ 224

  Fly    77 SSPEQLDLQYGSQMLARNSSQVARVAAIFVHPGYEP-----EDKYVNDIALLQLAQSVALSKFVQ 136
            :||..|.|               .|.|:..|.||.|     .::..|||||:.|:..:.|::::|
Human   225 ASPHGLQL---------------GVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQ 274

  Fly   137 PVRLPEPRQVTPGNASAVLAGWGLNATGGVVQQHLQKVKLQVFSDTEC--SERHQTYLHDSQICA 199
            ||.||...|.........:.|||.....|.....||:.::.:.|:..|  ::.:...:.....||
Human   275 PVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCA 339

  Fly   200 GLPEGGKGQCSGDSGGPLLLIGSDTQV------GIVSWSIKPCARPPFPGVFTEVSAYVDWIVET 258
            |.||||...|.||||||.:...|.::.      |||||. ..||....|||:|:||.:.:||.:.
Human   340 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG-TGCALAQKPGVYTKVSDFREWIFQA 403

  Fly   259 VNSYSPPSSLWVGQL 273
            :.::|..|.: |.||
Human   404 IKTHSEASGM-VTQL 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32808NP_726740.1 Tryp_SPc 30..258 CDD:238113 85/257 (33%)
HPNNP_002142.1 Hepsin-SRCR 51..159 CDD:462736
Tryp_SPc 163..400 CDD:238113 83/254 (33%)
Blue background indicates that the domain is not in the aligned region.

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