DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32808 and Klk1b4

DIOPT Version :9

Sequence 1:	NP_726740.1	Gene:	CG32808 / 318221	FlyBaseID:	FBgn0052808	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_035045.2	Gene:	Klk1b4 / 18048	MGIID:	97320	Length:	256	Species:	Mus musculus

Alignment Length:	233	Identity:	75/233 - (32%)
Similarity:	122/233 - (52%)	Gaps:	27/233 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 PFVVSLRRAKSGRHSCGATLLNPYWVLTAAHCVRGSSPEQLDLQYGSQMLARNSSQVARVAAIFV 106
            |:.|::.|  ..::.||..||:..||||||||.  :...|:.|...:.:....|.|...|:....
Mouse    32 PWHVAVYR--FNKYQCGGVLLDRNWVLTAAHCY--NDKYQVWLGKNNFLEDEPSDQHRLVSKAIP 92

  Fly   107 HPGY----------EPEDKYVNDIALLQLAQSVALSKFVQPVRLP--EPRQVTPGNASAVLAGWG 159
            ||.:          :|||.|.||:.||:|::...::..|:|:.||  ||:.    .::.:.:|||
Mouse    93 HPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKL----GSTCLASGWG 153

  Fly   160 LNATGGVVQQH---LQKVKLQVFSDTECSERHQTYLHDSQICAGLPEGGKGQCSGDSGGPLLLIG 221
              :|..:..::   ||.|.|::..:.:|.:.|:..:.|:.:|||..:||...|..||||||:..|
Mouse   154 --STTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDG 216

  Fly   222 SDTQVGIVSWSIKPCARPPFPGVFTEVSAYVDWIVETV 259
              ...||.||..:||..|..|.|:|::..:..||.||:
Mouse   217 --ILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETM 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32808	NP_726740.1	Tryp_SPc	29..255	CDD:214473	71/227 (31%)
CG32808	NP_726740.1	Tryp_SPc	30..258	CDD:238113	73/230 (32%)
Klk1b4	NP_035045.2	Tryp_SPc	13..251	CDD:238113	73/230 (32%)
Klk1b4	NP_035045.2	Activation peptide homolog	18..24
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837414
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4246
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.890