Protein Alignment ppk8 and scnn1b

DIOPT Version :10

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 665
• Identity: 131/665 - (19%)
• Similarity: 233/665 - (35%)
• Gaps: 183/665 - (27%)

  Fly     1 MRVPRNRQRAFF--ASQQKRSRPQHLQITLSTWRRILSRNTDEFCRNTTIHGLKYINNSKLRSSD 63
            :.|...|.:.:|  |..:.:..|.:....|..|          ||.||..||.|.|  .|.....
 Frog     2 LHVKMKRLKRYFTRALHRIQKGPGYTYKELLVW----------FCDNTNTHGPKRI--IKEGPKK 54

  Fly    64 RLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIV-----GIDPELT-SIANEPFPAVTICNLNQAL 122
            |:.:.|..||...|..         |....:|:     |:...|: ......|||||:||.|...
 Frog    55 RVMWFILTLVFAGLVF---------WQWGVLILTYLSYGVSVSLSIGFKTMEFPAVTVCNANPYK 110

  Fly   123 AERVEHFSND-----SVEFAMLQLLCRRKVDV-------ELVKTNDSRWEEF---ILNISQPCNS 172
            ..||:....|     :.....:|...:.:.:.       :.|..:.:.|...   :::.:.|.|.
 Frog   111 YSRVKPLLKDLDALVATALDRIQFSSQDQANTFTQSSTNQNVTLDPTLWNHIPLVVIDETDPSNP 175

  Fly   173 MVIHC-------------RFGADD-------YECARLFHPIVTDEGLCCVF-------NMLHPRF 210
            :|.:.             |..::|       |:.|.   .:.|:....||:       ..|...:
 Frog   176 IVNNIFDNNAIYSKNNSFRNSSEDQTSYSQRYKVAM---KLCTNNNTQCVYRNFTSGIQALQEWY 237

  Fly   211 MYR-----KRVPYSHRNISLPEGFHA--------------------------------VNWHAEL 238
            :.:     ..||.:.|   :..||.|                                .||..|
 Frog   238 LLQLSSIFSNVPLADR---IAMGFKAEDLILTCLFGGQPCSYRNFTRIYDADYGNCYIFNWGQE- 298

  Fly   239 GYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYCSSSSSIGFKIALHSPNESPNVRE 303
                      |::|:   .:...|...||.|.||::...|.....::...::.||.....|.|::
 Frog   299 ----------GEDPM---ASANPGADFGLKLVLDIEQGEYLPYVQTTAAARLILHQQRSFPFVKD 350

  Fly   304 TGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFH------NELKLRWFAHYTQRNCVAEC 362
            .|:...||.||.:     .:|.:: |.:::.....|..:      ..|...:.:.|:.::|:..|
 Frog   351 LGIYAMPGTETSI-----AVLVDQ-LEHMEAPYSSCTVNGSDIPVQNLYAEFNSSYSIQSCLRSC 409

  Fly   363 LSGWLIRHCGCVTFYMPRLNANDTICPLHKR----ECVELIRFRTIIAMESCLDECLPSCFDLSF 423
            ....:::.|||..:..|..|.:: .|...|.    .|...:| .::...|||:..|...|.|..:
 Frog   410 YQEQMVQTCGCADYQYPLPNGSE-YCSNDKYPDWVPCYYGLR-DSVADRESCISLCQQPCNDTQY 472

  Fly   424 SAIAYSTRISLDGFRETPSNGG--WNFTDAYVER-----------SVAVVNMYFKDPTFRANKQT 475
            ..:     ||:   .:.||.|.  |.|.....|:           .:..:|:||::..:|:..::
 Frog   473 KMV-----ISM---ADWPSAGAQDWIFHVLSYEKDSSHNITVNRNGIVRLNIYFQEFNYRSITES 529

  Fly   476 EFIGFSDFLSGVGGLMGLFLGFSFLSIAE-------CVYFALIRPCRTCSEIRQLNQ-------- 525
            |.......||.:||..|.::|.|.|.|.|       ||:..:::......:.||..|
 Frog   530 EATNVVWLLSNLGGQFGFWMGGSVLCIIEFGEIIIDCVWITILKLLAWIKDRRQRRQRAQYADPP 594

  Fly   526 PRVHQMNLKRSPTPG 540
            |.|.:: ::....||
 Frog   595 PTVSEL-VEAHTNPG 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:459966	117/580 (20%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	126/640 (20%)