DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk8 and ppk16

DIOPT Version :9

Sequence 1:	NP_001036260.3	Gene:	ppk8 / 318213	FlyBaseID:	FBgn0052792	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	NP_001334673.1	Gene:	ppk16 / 3885612	FlyBaseID:	FBgn0065108	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	539	Identity:	126/539 - (23%)
Similarity:	215/539 - (39%)	Gaps:	100/539 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RPQHLQITLSTWRRILSRNTDEFCRNTTIHGLKYINNSKLRSSDRLFFGIALLVVLSLAIYLIQD 84
            :|||....:..|   .:.|...:|:.|::||..||....:...:|.|:.:.:::.:..:|.|:..
  Fly    40 QPQHRFRQIGEW---FTENMRNYCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSIVLVVV 101

  Fly    85 AFDKWNTNPVIVGIDPELTSIANEPFPAVTICNLNQ-------ALAERVE----------H---- 128
            ::......|.:..|:.......|.|||||||||.|:       :|.::::          |
  Fly   102 SWYWSQETPTVTVIESSHFPTWNIPFPAVTICNFNKISKSKALSLLDQMQVPVGINRSELHNLFN 166

  Fly   129 ---------FSNDSVEFAMLQLLCRRKVDVELVKTNDSRWEEFILNISQPCNSMVIHCRFGADDY 184
                     .||||::          |.| .::..|:.........:|..|..|:..|.:...:.
  Fly   167 LTLLPVDTMISNDSLQ----------KYD-RILSLNNLTLNRLTQQLSPDCIEMISSCIWKGINT 220

  Fly   185 ECARLFHPIVTDEGLCCVFNMLHPRFMYRKRVPYSHRNISLPEGFHAVNWHAELGYRKRGFQPDG 249
            .|..||..|.|.||.||.||..                     |..:.|:..::.|:.
  Fly   221 RCESLFQRIDTMEGQCCTFNYF---------------------GGISNNFPEKIAYQV------- 257

  Fly   250 DNPLYPRRAQGTGESLGLSLTLDVQADAYYCSSSSSIGFKIALHSPNESPNVRETGVLLAPGMET 314
              |..|.|..|.|...|||:.|:.....||.:..|..||::.||.....|:......::....|:
  Fly   258 --PKRPYRVTGCGYPTGLSVLLNPMISDYYGTFFSGFGFRLLLHDAYNFPDENSETKVVTTTRES 320

  Fly   315 KLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLRWFAHYTQRNCVAECLSGWLIRHCGCVTFYMP 379
            .:||:|........:|.:|...|.|||.:|:.:.....|:..||:.||.....:..|||:..|:.
  Fly   321 FVRINPESTYATNDIRRMDLSLRNCLFGSEMTMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVY 385

  Fly   380 RLNANDTICPLHKRECV-----------ELIRFRTIIAMES----CLDECLPSCFDLSFSAIAYS 429
            . |.:..:|.:.:..|:           ..:.|...|..|:    |  .|||.|....:.:.:.:
  Fly   386 N-NGSYKVCGVLQTNCIIHSKRLFSHALANLNFSLSIVRETDSFPC--GCLPDCQSNHYVSESTT 447

  Fly   430 TRISLDGFRETPSNGGWNFTDAYVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLF 494
            .|:.:..|...|:..  |.||.      .:::::|.|......:...|..:...|:..|||:||.
  Fly   448 GRLDISYFANRPTFN--NATDR------ILLHVFFSDLMSTRYRTDIFQNWLSALASFGGLLGLI 504

  Fly   495 LGFSFLSIAECVYFALIRP 513
            :|||.::..|.:||...||
  Fly   505 MGFSIVTAFEFIYFLTFRP 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	117/510 (23%)
ppk16	NP_001334673.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456732
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000867
OrthoInspector	1	1.000	-	-		otm24766
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	9	8.740