DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk8 and ppk9

DIOPT Version :9

Sequence 1:	NP_001036260.3	Gene:	ppk8 / 318213	FlyBaseID:	FBgn0052792	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	NP_611622.2	Gene:	ppk9 / 37498	FlyBaseID:	FBgn0085398	Length:	599	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	114/531 - (21%)
Similarity:	192/531 - (36%)	Gaps:	151/531 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EFCRNTTIHGLKYINNSKLRSSDRL----FFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPE 101
            ||.:.::|||..|:....|...:|:    |..:||..::||:    :..:.::.|:|:::.:|..
  Fly   153 EFLQGSSIHGFIYLAKLGLSFVERVLWLAFICVALFSIISLS----KRTWHRFQTSPMVISMDRN 213

  Fly   102 LTSIANEPFPAVTICNLNQALAERVEHF----------SNDSVEFAMLQLLCRRKVDVELVKTND 156
             ..:.|..||::|:|...:....:||.:          ..|..:|        |...|:|.....
  Fly   214 -KLVWNTSFPSLTVCPHKRIDELKVEEYILAHPDQFLSEEDQEDF--------RDFIVKLASLTY 269

  Fly   157 SRWEEFILNISQPCNSMVIHCRFGADD-------YECARLFHPIV--------------TDEGLC 200
            ...|...||.|           :|...       ||....|.|.:              |:.|:|
  Fly   270 DNLETLPLNKS-----------YGIPSTKYLELLYELKWAFEPEISSGAAVKMFIYETQTEFGIC 323

  Fly   201 CVFNMLHPRFMYRKRVPYSHRNISLPEGFHAVNWHAELGYRKRGFQPDGD----NPLYPRRAQGT 261
            ...|.:..|:   ....|          :.:.:|         .....||    :||       .
  Fly   324 HSVNSMVARY---NSFDY----------WRSGDW---------SLMDHGDRVTVHPL-------D 359

  Fly   262 GESLGLSLTLDVQADAYYCSSSSSIGFKIALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTE 326
            ||.....:.|....|.|:             |...:.|::.:..........|.:.:...:|.|.
  Fly   360 GEIYAQIINLSTAYDVYF-------------HGAGDVPSISKQRYTFPESDYTTVELIALEIFTN 411

  Fly   327 KHLRNVDRRSRRCLFHNEL-KLRWFAHYTQRNCVAECLSGWLIRHCGCVT-FYMPRLNAND---- 385
            :..|...:||  |.|:.|. ::.....|:...|::||...:.:|.||||. ||..|...|.
  Fly   412 EEARATKQRS--CRFNYEAEEMMTVPIYSFGLCLSECRMFFALRVCGCVPHFYRNRCGYNHIFGT 474

  Fly   386 --------TICPLHKRECVELIRFRTIIAMES------CLDECLPSCFDLSFSAIAYSTRISLDG 436
                    .:|.|....|:..|: |.||:::|      |  .||.:|.|.:|...:|.:|:...|
  Fly   475 QMRNGRRLPVCGLEGIGCLVKIK-REIISLKSDKYKINC--NCLANCDDSNFFVQSYRSRVWFLG 536

  Fly   437 FRETPSNGGWNFTDAYVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLS 501
                 :|..|..               .:.|..:..::..| .|:|.|..:|||:|.|||.|.||
  Fly   537 -----ANLQWGI---------------LEHPKMQLRREVLF-SFADVLVYIGGLVGFFLGCSALS 580

  Fly   502 IAECVYFALIR 512
            ..|.:|:...|
  Fly   581 FTEIIYYFTAR 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	111/524 (21%)
ppk9	NP_611622.2	ASC	154..587	CDD:279230	111/524 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456742
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850