Protein Alignment ppk8 and Asic3

DIOPT Version :9

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: XP_038963092.1
• Gene: Asic3 / 286920
• RGDID: 708578
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 634
• Identity: 132/634 - (20%)
• Similarity: 204/634 - (32%)
• Gaps: 250/634 - (39%)

  Fly    42 FCRNTTIHGLKYI---NNSKLRSSDRLFFGI-ALLVVLSLAIYLIQDA--------------FDK 88
            |..:.|:|||.:|   ....||.      |: |..|:||||.:|.|.|              .|:
  Rat    21 FASSCTMHGLGHIFGPGGLTLRR------GLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDE 79

  Fly    89 WNTNPVIVGIDPELTSIANEPFPAVTICNLNQALAERV------------------EHFS----- 130
            ..::        :||      |||||:||:|.....|:                  ||.:
  Rat    80 RESH--------QLT------FPAVTLCNINPLRRSRLTPNDLHWAGTALLGLDPAEHAAYLRAL 130

  Fly   131 ---------NDSVEFAMLQLLCRRKVDVELVKTNDSRWEEFILNISQPCNSMVIHCRF-----GA 181
                     ..|..|.|.||..|....:|                     .|::.||:     |.
  Rat   131 GQPPAPPGFMPSPTFDMAQLYARAGHSLE---------------------DMLLDCRYRGQPCGP 174

  Fly   182 DDYECARLFHPIVTDEGLCCVFNMLHPRFMYRKRVPYSHRNISLPEGFHAVNWHAELGYRKRGFQ 246
            ::      |..|.|..|.|..||                      .|.|.    |||....:|
  Rat   175 EN------FTVIFTRMGQCYTFN----------------------SGAHG----AELLTTPKG-- 205

  Fly   247 PDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYC------SSSSSIGFKIALHSPNESPNVRETG 305
                         |.|.  ||.:.||||.:.|..      .:...:|.::.:||.:|.|.:.:.|
  Rat   206 -------------GAGN--GLEIMLDVQQEEYLPIWKDMEETPFEVGIRVQIHSQDEPPAIDQLG 255

  Fly   306 VLLAPGMET--------------------KLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLRWF 350
            ...|||.:|                    ...:||.....|........|.|..
  Rat   256 FGAAPGHQTFVSCQQQQLSFLPPPWGDCNTASLDPDDFDPEPSDPLGSPRPRPS----------- 309

  Fly   351 AHYTQRNCVAECLSGWLIRHCGCVTFYMPRLNANDTIC-PLHKRECVE-----LIRFRTIIAMES 409
            ..|:...|...|.|.::.|.|||...:||   .|..:| |...::|..     ::|..|.:
  Rat   310 PPYSLIGCRLACESRYVARKCGCRMMHMP---GNSPVCSPQQYKDCASPALDAMLRKDTCV---- 367

  Fly   410 CLDECLPSCFDLSFSAIAYSTRISLDGFRETPSNGGWNFTDAYVERSVAVVNMYFKDPTFRANKQ 474
            |.:.|..:.:....|.:...:|.|.......     :|.:::|:..:|.|::::|:...:.|.:|
  Rat   368 CPNPCATTRYAKELSMVRIPSRASARYLARK-----YNRSESYITENVLVLDIFFEALNYEAVEQ 427

  Fly   475 TEFIGFSDFLSGVGGLMGLFLGFSFLSIAE----------------------CV--YFALIRPCR 515
            ......|:.|..:||.||||:|.|.|:|.|                      |:  :...:.|.
  Rat   428 KAAYEVSELLGDIGGQMGLFIGASLLTILEILDYLCEVGKNPRHHGEESGHQCLKGWTGYLTPA- 491

  Fly   516 TCSEI-------------------------RQLNQPRVHQMNLKRSPTP 539
            ||.::                         .:||..|.|..:|...|.|
  Rat   492 TCPQVFQDRVLGYFWNRRSAQKRSGNTLLQEELNGHRTHVPHLSLGPRP 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	122/576 (21%)
Asic3	XP_038963092.1	ASC	17..547	CDD:413546	132/634 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345661
Domainoid	1	1.000	111	1.000	Domainoid score	I6095
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8907
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.750