DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk8 and ppk5

DIOPT Version :9

Sequence 1:	NP_001036260.3	Gene:	ppk8 / 318213	FlyBaseID:	FBgn0052792	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	NP_996138.2	Gene:	ppk5 / 2768987	FlyBaseID:	FBgn0053289	Length:	474	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	162/468 - (34%)
Similarity:	269/468 - (57%)	Gaps:	16/468 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 LKY-INNSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPELTSIANEPFPAVT 114
            ||| |:::......:|:|.|...:||.:|:.|....::||::.|||:||..::|.|...|||.:|
  Fly     4 LKYVISDNNYSWWIKLYFAIIFALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPIDQIPFPTIT 68

  Fly   115 ICNLNQALAERVEHFSNDSVEFAMLQLLCRRKVDVELVKTNDSR---WEEFILNISQPCNSMVIH 176
            :||:|||...:|||....|:.:||||..|.::.:.........|   :..|||::|:.|..:::.
  Fly    69 VCNMNQAKKSKVEHLMPGSIRYAMLQKTCYKESNFSQYMDTQHRNETFSNFILDVSEKCADLIVS 133

  Fly   177 CRFGADDYECARLFHPIVTDEGLCCVFNMLHPRFMYRKRVPYSHRNISLPEGFH--AVNWHAELG 239
            |.|......|..:|.....||||||:||:|||.::|:.:.||. |:.:..:.|.  ||:|....|
  Fly   134 CIFHQQRIPCTDIFRETFVDEGLCCIFNVLHPYYLYKFKSPYI-RDFTSSDRFADIAVDWDPISG 197

  Fly   240 YRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYCSSSSSIGFKIALHSPNESPNVRET 304
            |.:|  .|   :..|||...|.|.|:||.:.|:...|.|:|||::..||||.|::|.:.|.::|:
  Fly   198 YPQR--LP---SSYYPRPGVGVGTSMGLQIVLNGHVDDYFCSSTNGQGFKILLYNPIDQPRMKES 257

  Fly   305 GVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLRWFAHYTQRNCVAECLSGWLIR 369
            |:.:..|.:|..||....:.....:||:.|..|:|:|.:|.:|.::.:||:|||.|||.|.:.:|
  Fly   258 GLPVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELLFYRYYTRRNCEAECDSMFFLR 322

  Fly   370 HCGCVTFYMPRLNANDTICPLHKRECVELIRFRTIIAMES--CLDECLPSCFDLSFSAIAYSTRI 432
            .|.|:.:|:|.:..|.::|.:...||:.....: |..::|  |.:.||.||.||.|...|:||..
  Fly   323 LCSCIPYYLPLIYPNASVCDVFHFECLNRAESQ-IFDLQSSQCKEFCLTSCHDLIFFPDAFSTPF 386

  Fly   433 SLDGFRETPSNGGWNFTDAYVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGF 497
            |....: ..:|...||:..|:.:::||||.:..|..||::.:|.:.|.:::::..||:|.|.:||
  Fly   387 SQKDVK-AQTNYLTNFSSEYMRKNLAVVNFFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGF 450

  Fly   498 SFLSIAECVYFAL 510
            |.:.:||.:|..|
  Fly   451 SVIFLAEIIYIIL 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	160/464 (34%)
ppk5	NP_996138.2	ASC	4..460	CDD:279230	160/463 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469315
Domainoid	1	1.000	101	1.000	Domainoid score	I6864
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4956
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D112386at6656
OrthoFinder	1	1.000	-	-		FOG0000867
OrthoInspector	1	1.000	-	-		mtm8412
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	11	10.800