Protein Alignment ppk8 and Scnn1g

DIOPT Version :9

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_058742.2
• Gene: Scnn1g / 24768
• RGDID: 3641
• Length: 650
• Species: Rattus norvegicus
• Alignment Length: 677
• Identity: 126/677 - (18%)
• Similarity: 214/677 - (31%)
• Gaps: 261/677 - (38%)

  Fly    42 FCRNTTIHGLKYINNSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPELTSIA 106
            :|.||..||.:.|..|:.|....|:....|..|   |:.:.|.|...::...|.|.|......:
  Rat    32 YCMNTNTHGCRRIVVSRGRLRRLLWIAFTLTAV---ALIIWQCALLVFSFYTVSVSIKVHFQKL- 92

  Fly   107 NEPFPAVTICNLN----QALAERVEHFSNDSVE-------------------------------F 136
              .||||||||:|    .|:::.:....:::.:                               |
  Rat    93 --DFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKESRKRREAGSMPSTLEGTPPRFF 155

  Fly   137 AMLQLLC----------------RRKVDVELVK--------------------TNDS-------- 157
            .::.||.                :||:..:::.                    :||:
  Rat   156 KLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGFQLCSNDTSDCATYTF 220

  Fly   158 --------RWE-------------EFILNISQPCNSMVIHCRFGADDYEC-ARLF----HPIVTD 196
                    .|.             |..:|:|.....:::.|.|  |...| ||.|    ||:.
  Rat   221 SSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAKELLVTCFF--DGMSCDARNFTLFHHPMY-- 281

  Fly   197 EGLCCVFNMLHPRFMYRKRVPYSHRNISLPEGFHAVNWHAELGYRKRGFQPDGDNPLYPRRAQGT 261
             |.|..||                                           :.:|......:.|
  Rat   282 -GNCYTFN-------------------------------------------NKENATILSTSMG- 301

  Fly   262 GESLGLSLTLDVQADAYYCSSSSSIGFKIALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTE 326
            |...||.:.|.:..|.|.....||.|.|:.:|..||.|.:.:.|:.:...|.|.:.:.    |||
  Rat   302 GSEYGLQVILYINEDEYNPFLVSSTGAKVLIHQQNEYPFIEDVGMEIETAMSTSIGMH----LTE 362

  Fly   327 KHLRNVDRRSRRCL----------FHNELKLRWFAHYTQRNCVAECLSGWLIRHCGCVTFYMPRL 381
            ..  .:.....:|.          .:|       |.|:.:.|:..|....::..|||..:..| |
  Rat   363 SF--KLSEPYSQCTEDGSDVPVTNIYN-------AAYSLQICLYSCFQTKMVEKCGCAQYSQP-L 417

  Fly   382 NANDTICPLHKRE----CVELIRFRTIIAME-SCLDECLPSCFDLSFSAIAYSTRISLDGFRETP 441
            ......|...:..    |...: ::..:..| .|...|..||   ||.....:|.::     :.|
  Rat   418 PPAANYCNYQQHPNWMYCYYQL-YQAFVREELGCQSVCKQSC---SFKEWTLTTSLA-----QWP 473

  Fly   442 SNGG---------W----------NFTDAYVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGV 487
            |...         |          |.||      :|.:.:::||...|:..::........||..
  Rat   474 SEASEKWLLNVLTWDQSQQINKKLNKTD------LAKLLIFYKDLNQRSIMESPANSIEMLLSNF 532

  Fly   488 GGLMGLFLGFSFLSIAECV------YFALIRPCRTCSEIRQLNQPRVHQMNLKRSPTPGNIRYIS 546
            ||.:||::..|.:.:.|.:      :|::|..       ||.::
  Rat   533 GGQLGLWMSCSVVCVIEIIEVFFIDFFSIIAR-------RQWHK--------------------- 569

  Fly   547 AADWF---QAELAHQQPNNRQ-HFNPA 569
            |.||:   |...:.:.|::|| ..|||
  Rat   570 AKDWWARRQTPPSTETPSSRQGQDNPA 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	112/610 (18%)
Scnn1g	NP_058742.2	ENaC	24..631	CDD:273304	126/677 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	577..628		7/20 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345665
Domainoid	1	1.000	111	1.000	Domainoid score	I6095
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I4773
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8907
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.700