Protein Alignment ppk8 and Asic4

DIOPT Version :9

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: XP_036020902.1
• Gene: Asic4 / 241118
• MGIID: 2652846
• Length: 586
• Species: Mus musculus
• Alignment Length: 615
• Identity: 135/615 - (21%)
• Similarity: 219/615 - (35%)
• Gaps: 194/615 - (31%)

  Fly    37 RNTDEFCRNTTIHGLKYINNSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPE 101
            |:...|...:|:|||............|..:.:|||..|:..:|........:.|.|.:|.:||
Mouse    40 RDLATFASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAASLARGYLTRPHLVAMDP- 103

  Fly   102 LTSIANEP---FPAVTICNLNQ----ALAER-VEHFSN---------DSVEFAMLQLLCRRKVDV 149
               .|..|   |||||:||:|:    ||::. :.|.:|         |....|.|:......||:
Mouse   104 ---AAPAPVAGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDI 165

  Fly   150 ELVKTNDSRWEEFILNISQPCNSMVIHCRFGADDYECARLFHPIVTDEGLCCVFNMLHPRFMYRK 214
             |.:|...     :.::.:.||....||        .|..|..:.|..|.|..||
Mouse   166 -LNRTGHQ-----LADMLKSCNFSGHHC--------SASNFSVVYTRYGKCYTFN---------- 206

  Fly   215 RVPYSHRNISLPEGFHAVNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYY 279
                                            .|..:.| |.||.|.|.  ||.:.||:|.:.|.
Mouse   207 --------------------------------ADPQSSL-PSRAGGMGS--GLEIMLDIQQEEYL 236

  Fly   280 ------CSSSSSIGFKIALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRR 338
                  ..:|...|.::.:||..|.|.:.:.|..::||.:|.:...      |:.|..:.:....
Mouse   237 PIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQ------EQRLTYLPQPWGN 295

  Fly   339 CLFHNELK---LRWFAHYTQRNCVAECLSGWLIRHCGCVTFYMP--------------------- 379
            |...:||:   |:.::.|:...|...|....:::.|.|...:||
Mouse   296 CRAESELREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPGGHLQPVFGATLLSSRTSRRQ 360

  Fly   380 --------RL---------------NANDTICPLHKRECVELIRFRTIIAMESCLDECLPS---- 417
                    |:               ..|:||||.:             |.:| |.|..|.|
Mouse   361 RCMRTTCTRIYTHERVLMCMSGYLHMGNETICPPN-------------IYIE-CADHTLDSLGGG 411

  Fly   418 ----CF-DLSFSAIAYSTRISLDGFRETPSNGG-------WNFTDAYVERSVAVVNMYFKDPTFR 470
                || ....:...|...||:   .:.|:.|.       :|..:.|:..:..|::::|:..|..
Mouse   412 SEGPCFCPTPCNLTRYGKEISM---VKIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSE 473

  Fly   471 ANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAECVYFALIRPCRTCSEIRQLNQPRVHQMNLKR 535
            |.:|....|.|..|..:||.||||:|.|.|::.|.:.:           |.:::..|:.:: .:|
Mouse   474 AMEQQAAYGLSALLGDLGGQMGLFIGASILTLLEILDY-----------IYEVSWDRLKRV-WRR 526

  Fly   536 SPTP-----GNIRYISAADWFQAELAHQQP 560
            ..||     |.|..:..     .||..|.|
Mouse   527 PKTPLRTSTGGISTLGL-----QELKEQSP 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	123/551 (22%)
Asic4	XP_036020902.1	ASC	40..535	CDD:413546	129/592 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842239
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.740