Protein Alignment ppk8 and Scnn1g

DIOPT Version :9

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_035456.1
• Gene: Scnn1g / 20278
• MGIID: 104695
• Length: 655
• Species: Mus musculus
• Alignment Length: 588
• Identity: 119/588 - (20%)
• Similarity: 201/588 - (34%)
• Gaps: 170/588 - (28%)

  Fly    42 FCRNTTIHGLKYINNSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPELTSIA 106
            :|.||..||.:.|..|:.|....|:....|..|   |:.:.|.|...::...|.|.|......:
Mouse    32 YCLNTNTHGCRRIVVSRGRLRRLLWIAFTLTAV---ALIIWQCALLVFSFYTVSVSIKVHFQKL- 92

  Fly   107 NEPFPAVTICNLN----QALAERVEHFSNDSVEFAMLQLLCRRKV-DVELVKTND-----SRWE- 160
              .||||||||:|    .|:::.:....:::.: |:|.|...:.| |....|..:     |.||
Mouse    93 --DFPAVTICNINPYKYSAVSDLLTDLDSETKQ-ALLSLYGVKDVLDSTPRKRREAGSMRSTWEG 154

  Fly   161 -----------------------EFILNISQPCNSMVIHCRFGADD----YECARL--FHPIVTD 196
                                   :|.....:..:..:||   .|.:    :|..:|  |.....|
Mouse   155 TPPRFLNLIPLLVFNENEKGKARDFFTGRKRKISGKIIH---KASNVMHVHESKKLVGFQLCSND 216

  Fly   197 EGLCCVFNMLHPRFMYRKRVPYSHRNISLPEGF--HAVNWHAELGYRKR---------------- 243
            ...|..:.             :|....::.|.:  |.:|..|::...|:
Mouse   217 TSDCATYT-------------FSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFF 268

  Fly   244 -GFQPDGDN------PLY------PRRAQGT-------GESLGLSLTLDVQADAYYCSSSSSIGF 288
             |...|..|      |:|      ..|...|       |...||.:.|.:..|.|.....||.|.
Mouse   269 DGMSCDARNFTLFHHPMYGNCYTFNNRENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGA 333

  Fly   289 KIALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCL----------FHN 343
            |:.:|..||.|.:.:.|..:...|.|.:.:.    |||..  .:.....:|.          .:|
Mouse   334 KVLVHQQNEYPFIEDVGTEIETAMSTSIGMH----LTESF--KLSEPYSQCTEDGSDVPVTNIYN 392

  Fly   344 ELKLRWFAHYTQRNCVAECLSGWLIRHCGCVTFYMPRLNANDTICPLHKRE----CVELIRFRTI 404
                   |.|:.:.|:..|....::..|||..:..| |......|...:..    |...: ::..
Mouse   393 -------AAYSLQICLYSCFQTKMVEKCGCAQYSQP-LPPAANYCNYQQHPNWMYCYYQL-YQAF 448

  Fly   405 IAME-SCLDECLPSCFDLSFSAIAYSTRISLDGFRETPSNGG---------W----------NFT 449
            :..| .|...|..||   ||.....:|.::     :.||...         |          |.|
Mouse   449 VREELGCQSVCKQSC---SFKEWTLTTSLA-----QWPSEASEKWLLNVLTWDQSQQINKKLNKT 505

  Fly   450 DAYVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAECV------YF 508
            |      :|.:.:::||...|:..::........||..||.:||::..|.:.:.|.:      :|
Mouse   506 D------LAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFF 564

  Fly   509 ALI 511
            ::|
Mouse   565 SII 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	117/583 (20%)
Scnn1g	NP_035456.1	ENaC	24..636	CDD:273304	119/588 (20%)
		deg-1	32..557	CDD:273309	117/576 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	582..636

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842235
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.650