Protein Alignment ppk8 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001258952.1
• Gene: Scnn1b / 20277
• MGIID: 104696
• Length: 638
• Species: Mus musculus
• Alignment Length: 596
• Identity: 121/596 - (20%)
• Similarity: 215/596 - (36%)
• Gaps: 177/596 - (29%)

  Fly    42 FCRNTTIHGLKYI--NNSKLRSSDRLFFGIAL----LVVLSLAIYLIQDAFDKWNTNPVIVGIDP 100
            :|.||..||.|.|  ...|.::   ::|.:.|    ||.....:::  ..:..|.   |.|.:..
Mouse    29 YCNNTNTHGPKRIICEGPKKKA---MWFLLTLLFACLVCWQWGVFI--QTYLSWE---VSVSLSM 85

  Fly   101 ELTSIANEPFPAVTICNLNQALAERVEHFSNDSVEFAMLQLLCRRKVDVELVKTNDSRWEEF--- 162
            ...::   .|||||:||.:.....:|:|...|..|  :::.:..:.:..|...:|.:|...|
Mouse    86 GFKTM---NFPAVTVCNSSPFQYSKVKHLLKDLDE--LMEAVLEKILAPEASHSNTTRTLNFTIW 145

  Fly   163 -----------------ILNI-------SQP-----CNSMVIHCRF-----GADDYEC------- 186
                             :||:       |.|     ||:.  .|:.     .|:...|
Mouse   146 NHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQ--GCKVAMRLCSANGTVCTLRNFTS 208

  Fly   187 -------------ARLFHPIVTDE----G-------LCCVFNMLHPRFMYRKRVPYSHRN---IS 224
                         ..:|..::..:    |       |.|:|.          ..|.||||   |.
Mouse   209 ATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFG----------TEPCSHRNFTPIF 263

  Fly   225 LPE--GFHAVNWHAELGYRKRGFQPD---GDNPLYPRRAQGTGESLGLSLTLDVQADAYYCSSSS 284
            .|:  ..:..||         |...:   ..||         |...||.|.||:..:.|....:|
Mouse   264 YPDYGNCYIFNW---------GMTEETLPSANP---------GTEFGLKLILDIGQEDYVPFLAS 310

  Fly   285 SIGFKIALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLR- 348
            :.|.::.||.....|.:||.|:....|.||.:     .:|.:|..|..:..|...:..:::.::
Mouse   311 TAGARLMLHEQRTYPFIREEGIYAMAGTETSI-----GVLVDKLQRKGEPYSPCTMNGSDVAIKN 370

  Fly   349 ----WFAHYTQRNCVAECLSGWLIRHCGCVTFYMPRLNANDTICPLHKRE------CVELIRFRT 403
                :...|:.:.|:..|....:||:|.|..:..| |...:..|  :.|:      |...::. :
Mouse   371 LYSVYNTTYSIQACLHSCFQDHMIRNCSCGHYLYP-LPEGEKYC--NNRDFPDWAYCYLNLQM-S 431

  Fly   404 IIAMESCLDECLPSCFDLSFSAIAYSTRISLDGFRETPSNGG--W-------------NFTDAYV 453
            :...|:||..|..||.|..     |...||:   .:.||...  |             |.|  ..
Mouse   432 VTQRETCLSMCKESCNDTQ-----YKMTISM---ADWPSEASEDWILHVLSQERDQSSNIT--LS 486

  Fly   454 ERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAE-------CVYFALI 511
            .:.:..:|:||::..:|..:::........||.:||..|.::|.|.|.:.|       .::..:|
Mouse   487 RKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFIWITII 551

  Fly   512 RPCRTCSEIRQ 522
            :...:|..:|:
Mouse   552 KLVASCKGLRR 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	118/580 (20%)
Scnn1b	NP_001258952.1	ENaC	21..621	CDD:273304	121/596 (20%)
		deg-1	29..538	CDD:273309	117/570 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	594..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842211
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.650