Protein Alignment ppk8 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_035454.2
• Gene: Scnn1a / 20276
• MGIID: 101782
• Length: 700
• Species: Mus musculus
• Alignment Length: 564
• Identity: 118/564 - (20%)
• Similarity: 202/564 - (35%)
• Gaps: 139/564 - (24%)

  Fly    42 FCRNTTIHGLKYINNSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPELTSIA 106
            ||.||||||...:..||.......|:.:..|....:..:.....|:::.:.||.:.|:.....:.
Mouse    88 FCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYFSYPVSLNINLNSDKLV 152

  Fly   107 NEPFPAVTICNLNQALAERVEHFSNDSVEFAML-----------------QLLCRRKVDVEL--- 151
               |||||:|.||   ..|......|..|...:                 |...||:...:|
Mouse   153 ---FPAVTVCTLN---PYRYTEIKEDLEELDRITEQTLFDLYKYNSSYTRQAGGRRRSTRDLRGA 211

  Fly   152 --------------------------VKTNDSRWEEFILNIS-QPCNSMVIHCRF-----GADDY 184
                                      |:.|:.:.:.....|. |.||.....|.:     |.|..
Mouse   212 LPHPLQRLRTPPPPNPARSARSASSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAV 276

  Fly   185 ECARLFH------------PIVTDEGL-----CCVFNMLHPRFMYRKRVPYSHRNISLPEGFHAV 232
            .....||            |.:.:|.|     .|.||          :.|.:..|.|   .||
Mouse   277 REWYRFHYINILSRLPDTSPALEEEALGSFIFTCRFN----------QAPCNQANYS---QFH-- 326

  Fly   233 NWHAELG--YRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYCSSSSSIGFKIALHSP 295
              |...|  |.   |....::.|:.....|...  ||||||..:.:.:....|:..|.::.:|..
Mouse   327 --HPMYGNCYT---FNNKNNSNLWMSSMPGVNN--GLSLTLRTEQNDFIPLLSTVTGARVMVHGQ 384

  Fly   296 NESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFHNE---LKLRWFAHYTQRN 357
            :|...:.:.|..:.||:||.:.      :.::.|.::......|..:..   :|..:.:.|||:.
Mouse   385 DEPAFMDDGGFNVRPGVETSIS------MRKEALDSLGGNYGDCTENGSDVPVKNLYPSKYTQQV 443

  Fly   358 CVAECLSGWLIRHCGCVTFYMPRLNANDTICPLHKRE----CVELIRFRTIIAMES--CLDECLP 416
            |:..|....:|:.|||...:.|:....: .|...|:.    |  ..:.:...:::|  |..:|..
Mouse   444 CIHSCFQENMIKKCGCAYIFYPKPKGVE-FCDYLKQSSWGYC--YYKLQAAFSLDSLGCFSKCRK 505

  Fly   417 SCFDLSFSAIAYSTRISLDGFRETPS--NGGW---------NFTDAYVERSVAVVNMYFKDPTFR 470
            .|...::...|        |:...||  :..|         |:|.......||.:|::||:..::
Mouse   506 PCSVTNYKLSA--------GYSRWPSVKSQDWIFEMLSLQNNYTINNKRNGVAKLNIFFKELNYK 562

  Fly   471 ANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSI---AECVYFALI 511
            .|.::..:.....||.:|....|:.|.|.||:   ||.::..|:
Mouse   563 TNSESPSVTMVSLLSNLGSQWSLWFGSSVLSVVEMAELIFDLLV 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	117/559 (21%)
Scnn1a	NP_035454.2	ENaC	80..677	CDD:273304	118/564 (21%)
		deg-1	88..600	CDD:273309	116/556 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842243
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	107	1.000	Inparanoid score	I4904
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.800