Protein Alignment ppk8 and asic-2

DIOPT Version :9

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 103/525 - (19%)
• Similarity: 195/525 - (37%)
• Gaps: 113/525 - (21%)

  Fly    41 EFCRNTTIHGLKYINNSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPELTSI 105
            :|...:|:..:.::.|:..:.| |:|:....|.||.:..|.:.....|:.:.|..|.     |.|
 Worm    12 DFSNWSTVAVVPHVANANNKIS-RIFWIAIFLFVLGMFAYELYILIAKFFSYPATVN-----TEI 70

  Fly   106 ANEP--FPAVTICNLNQALAERVEHFSNDSVEFAMLQLLCRRKVDVELVKTNDSRW-------EE 161
            ..|.  ||.||:||:|......|:  ||.:  |:.:..|.....|..:...:..:|       |.
 Worm    71 LFEKQIFPVVTVCNMNPYKYSVVK--SNSA--FSSVNTLMTTYSDATVGTFSTDKWGLYADNDET 131

  Fly   162 FILNISQPCNSMVIHCRFGADDYECARL--FHPIVTDEGLCCVFNMLHPRFMYRKRVPYSHRNIS 224
            :.|: |:..:::|:.....:|..:...|  :..::.|    |.|          ..:|.|..:.:
 Worm   132 YDLD-SRAADALVLEANLISDTAKVPALYTYADLIQD----CSF----------AGIPCSESDFT 181

  Fly   225 -----LPEGFHAVNWHAELGY--RKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDV-----QADA 277
                 :....::.|..|.|.|  .:.|.|                  .||.|.|.|     ..:.
 Worm   182 KFIDPVYGACYSFNEDASLNYSVSREGIQ------------------FGLKLMLTVTQTKTNGNT 228

  Fly   278 YYCSSSSSIGFKIALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTEK--HLRNVDRRSRRCL 340
            ....::...|.:|.::|...||.:...|:....|.|:.:.:..::.:..|  :...|||......
 Worm   229 DSLPTTKLAGARIGVNSRGSSPGLDSNGIDAGVGYESAVSVSLTQNVRAKKPYGTCVDREPDSSD 293

  Fly   341 FHNELKLRWFAHYTQRNCVAECLSGWLIRHCGCVTFYMPR--LNANDTICPLHKR--ECVELIRF 401
            ::.:.      .||...|...|.....|..|.|..   ||  |.:.||.|...|.  :|::.::.
 Worm   294 YYKDF------IYTLETCFNGCKQRDTIAKCQCAN---PRLALGSTDTACQPIKADLDCLQTLKG 349

  Fly   402 R------TIIAMESCLDECLPSCFDLSFSAIAYSTRISLDGF---------RETPSNGGWNFTDA 451
            .      .|..:..|  .|.|.|.:.:     |:..:||..|         ..|...|..:.|::
 Worm   350 NQTSSTPNIDLLVEC--NCNPPCDEST-----YTPTVSLAQFPSTSYYVATSSTAGVGSCSSTNS 407

  Fly   452 ----------YVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAECV 506
                      :...:..::.::.:..::....:|.....|:.::.:||..||:||.|.:|:.|..
 Worm   408 KFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETAGYTVSNVINDLGGQAGLWLGLSVISVVEMT 472

  Fly   507 YFALI 511
            ...|:
 Worm   473 GLMLV 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	102/519 (20%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	102/520 (20%)
		ASC	13..471	CDD:279230	101/516 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28677
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730