Protein Alignment ppk8 and mec-4

DIOPT Version :10

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_510712.2
• Gene: mec-4 / 181728
• WormBaseID: WBGene00003168
• Length: 768
• Species: Caenorhabditis elegans
• Alignment Length: 694
• Identity: 128/694 - (18%)
• Similarity: 216/694 - (31%)
• Gaps: 265/694 - (38%)

  Fly    41 EFCRNTTIHGLKYINNSKLRSSDRLFFGIALLVVLSLA----IYL-IQDAFDKWNTNPVIVGIDP 100
            |||..|:.||:..|.     .:..:::. |:.|||.|.    :|| .|...||:|.|..||.|..
 Worm    86 EFCYKTSAHGIPMIG-----EAPNVYYR-AVWVVLFLGCMIMLYLNAQSVLDKYNRNEKIVDIQL 144

  Fly   101 ELTSIANEPFPAVTICNLN---QALAERVE----------------------------------- 127
            :..:   .||||:|:||||   .:||..|:
 Worm   145 KFDT---APFPAITLCNLNPYKASLATSVDLVKRTLSAFDGAMGKAGGNKDHEEEREVVTEPPTT 206

  Fly   128 --------------HFSNDSVEFAMLQLLC-----------RRKVDVELVKTN----------DS 157
                          ..|....|....:.||           ..:.:.||::|.          |.
 Worm   207 PAPTTKPARRRGKRDLSGAFFEPGFARCLCGSQGSSEQEDKDEEKEEELLETTTKKVFNINDADE 271

  Fly   158 RW---EEFI--------------LNISQPCNSMVIHCRFGADDYECARLFHPIVTDEGLCCVFN- 204
            .|   ||:.              :|:.:.|.|            |..:...|...|:...|.|:
 Worm   272 EWDGMEEYDNEHYENYDVEATTGMNMMEECQS------------ERTKFDEPTGFDDRCICAFDR 324

  Fly   205 MLH---PRFM-------------------YRKRVPYSHRN--ISLPEGFHAVNWHAEL------G 239
            ..|   |.|:                   ...:....||:  |..|..| .|.::.:.      .
 Worm   325 STHDAWPCFLNGTWETTECDTCNEHAFCTKDNKTAKGHRSPCICAPSRF-CVAYNGKTPPIEIWT 388

  Fly   240 YRKRGFQPDGDNPLYPRRAQGTGESLG-----------------------LSLT----------- 270
            |.:.|...:..|.|.....||..:.:.                       ||.|
 Worm   389 YLQGGTPTEDPNFLEAMGFQGMTDEVAIVTKAKENIMFAMATLSMQDRERLSTTKRELVHKCSFN 453

  Fly   271 ---LDVQAD------------------------------------------AYYCSSSSSIGFKI 290
               .|::||                                          :.|..::.:.|.::
 Worm   454 GKACDIEADFLTHIDPAFGSCFTFNHNRTVNLTSIRAGPMYGLRMLVYVNASDYMPTTEATGVRL 518

  Fly   291 ALHSPNESPNVRETGVLLAPGMETK--LRIDPSKILTEKHLRNV-DRRSRRCLFHNELKLRWFAH 352
            .:|...:.|.....|.....|..:.  ||:.....|...:...| |.::...::.|       ..
 Worm   519 TIHDKEDFPFPDTFGYSAPTGYVSSFGLRLRKMSRLPAPYGDCVPDGKTSDYIYSN-------YE 576

  Fly   353 YTQRNCVAECLSGWLIRHCGC--VTFYMPRLNAN--DTICPLHKRECVELIRFRTIIAMES---- 409
            |:...|...|....:::.|.|  ..|.:|. ||.  |...|: .|:|:: .|...:..:..
 Worm   577 YSVEGCYRSCFQQLVLKECRCGDPRFPVPE-NARHCDAADPI-ARKCLD-ARMNDLGGLHGSFRC 638

  Fly   410 -CLDECLPSCFDLSFSAIAY---STRISLDGFRETPSNGGWNFT----DAYVERSVAVVNMYFKD 466
             |...|..|.:.:::|...:   |.:|.|         |..|.|    :.:.:.:.|:|.::::.
 Worm   639 RCQQPCRQSIYSVTYSPAKWPSLSLQIQL---------GSCNGTAVECNKHYKENGAMVEVFYEQ 694

  Fly   467 PTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAECVYFAL 510
            ..|....::|..||.:.|:..||.:||:.|.|||:..|.|:..|
 Worm   695 LNFEMLTESEAYGFVNLLADFGGQLGLWCGISFLTCCEFVFLFL 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:459966	126/689 (18%)
mec-4	NP_510712.2	deg-1	86..736	CDD:273309	127/690 (18%)