Protein Alignment ppk8 and mec-10

DIOPT Version :10

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_509438.1
• Gene: mec-10 / 181101
• WormBaseID: WBGene00003174
• Length: 724
• Species: Caenorhabditis elegans
• Alignment Length: 731
• Identity: 126/731 - (17%)
• Similarity: 215/731 - (29%)
• Gaps: 326/731 - (44%)

  Fly    27 TLSTWRRILSRNTDEFCRNTTIHGLKYIN---NSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDK 88
            |..::|..:..:..:||..|:.||:..:.   ||..|::......|..:..::.|:.:||    |
 Worm    85 TRLSYRERIRWHLQQFCYKTSSHGIPMLGQAPNSLYRAAWVFLLLICAIQFINQAVAVIQ----K 145

  Fly    89 WNTNPVIVGIDPELTSIANEPFPAVTICNLN--------------------------------QA 121
            :.....|..|..:..:   .||||:|:||||                                :|
 Worm   146 YQKMDKITDIQLKFDT---APFPAITLCNLNPYKDSVIRSHDSISKILGVFKSVMKKAGDSSSEA 207

  Fly   122 LAE-------------------------------------------------------------- 124
            |.|
 Worm   208 LEEEEETEYDMNGITIQAKRKKRGAGEKGTFEPANSACECDEEDGSNECEERSTEKPSGDNDMCI 272

  Fly   125 --------------RVEHFSNDSVEFAMLQLLCRRKVD-----VELVKTN---DSR--------- 158
                          |.|.::|.:.:......||.:|..     .||.|..   :|:
 Worm   273 CAFDRQTNDAWPCHRKEQWTNTTCQTCDEHYLCSKKAKKGTKRSELKKEPCICESKGLFCIKHEH 337

  Fly   159 -------WEEF------------------------------------------------ILNISQ 168
                   ||.|                                                || :||
 Worm   338 AAMVLNLWEYFGDSEDFSEISTEEREALGFGNMTDEVAIVTKAKENIIFAMSALSEEQRIL-MSQ 401

  Fly   169 PCNSMVIHCRFGA------DDYECARLFHPIVTDE--GLCCVFNMLHPRFMYRKRVPYSHRNISL 225
            ..::::..|.|..      .|:|       :|.|.  |.|.|||  |.|.:::..|
 Worm   402 AKHNLIHKCSFNGKPCDIDQDFE-------LVADPTFGNCFVFN--HDREIFKSSV--------- 448

  Fly   226 PEGFHAVNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYCSSSSSIGFKI 290
                                           ||   |...||.:.|.|.| :.|..:|.::|.::
 Worm   449 -------------------------------RA---GPQYGLRVMLFVNA-SDYLPTSEAVGIRL 478

  Fly   291 ALHSPNESP------NVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSR------RCLFHN 343
            .:|..::.|      ....||.:.:.||..|                  :.||      .|:...
 Worm   479 TIHDKDDFPFPDTFGYSAPTGYISSFGMRMK------------------KMSRLPAPYGDCVEDG 525

  Fly   344 ELK---LRWFAHYTQRNCVAECLSGWLIRHCGCVTFYMPRLNANDTICPL-----HKRECVE--- 397
            ...   .:.:| |:...|...|....:|..|||..   ||..:...:.|.     :.|||:|
 Worm   526 ATSNYIYKGYA-YSTEGCYRTCFQELIIDRCGCSD---PRFPSIGGVQPCQVFNKNHRECLEKHT 586

  Fly   398 --------LIRFRTIIAMESCLDECLPSCFDLSFSAIAYSTR---ISLDGFRETPSNGGWNFTDA 451
                    ..:.|       |...|..:.:..|:|...:.::   ||| |..|..:.   ...:.
 Worm   587 HQIGEIHGSFKCR-------CQQPCNQTIYTTSYSEAIWPSQALNISL-GQCEKEAE---ECNEE 640

  Fly   452 YVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAE--CVYFALIRPC 514
            |.| :.|::.::::...|....::|..|....::..||.:||:.|.|.::..|  |:.|.||
 Worm   641 YKE-NAAMLEVFYEALNFEVLSESEAYGIVKMMADFGGHLGLWSGVSVMTCCEFVCLAFELI--- 701

  Fly   515 RTCSEIRQLNQPRVHQ 530
             ..:....:||.|:.:
 Worm   702 -YMAIAHHINQQRIRR 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:459966	118/692 (17%)
mec-10	NP_509438.1	deg-1	99..696	CDD:273309	117/691 (17%)