Protein Alignment ppk8 and unc-8

DIOPT Version :9

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001294293.1
• Gene: unc-8 / 177494
• WormBaseID: WBGene00006748
• Length: 778
• Species: Caenorhabditis elegans
• Alignment Length: 737
• Identity: 132/737 - (17%)
• Similarity: 217/737 - (29%)
• Gaps: 332/737 - (45%)

  Fly    14 SQQKRSRPQ----HLQITLSTWRRILSRNTDEFCRNTTIHGLKYINNSKLRSSDRLFFG------ 68
            |.:|..|.|    |.....|.|        .:||..|:.||:.|:..|.       |||
 Worm    84 SSRKSLRSQKIDYHTTTIKSLW--------FDFCARTSSHGIPYVATSS-------FFGRYVWAA 133

  Fly    69 --IALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPELTSIANEPFPAVTICNLN------------ 119
              :.:|:...|..|.....:.::.|   |:.:..:..:.|   |||.|:||||
 Worm   134 LFMCMLMAFLLQTYWTMSEYLQYRT---IIEMQLQFEAAA---FPAATVCNLNAFKYSELTQYEE 192

  Fly   120 ----------------------------QALAERVEH----------FSNDSVEFAMLQ------ 140
                                        :|::.|.:.          ..::.:|.|:.|
 Worm   193 IKEGFDYWERVINARMMSDSMKPGGDILEAISVRKKRSKSRDQLLFPIDDEDLEGAVYQPVFVRC 257

  Fly   141 -------------------LLCRRKVDV------------------------------------- 149
                               .:|....||
 Worm   258 TCMNMEQCVPNRNPLEVNASICMCFEDVTRGLIWPCYPTSVWTVKKCSGCSISNTCPDPDGPNAS 322

  Fly   150 -ELVKTN--------------------DSRW-----------------------EEFIL------ 164
             ::.|.|                    :.||                       |.|.|
 Worm   323 KQIAKHNSPLPCLCQSISHHCMVHPKDEIRWWNPNNYTVYSVTEPPTTEITETEEAFGLSDLKDA 387

  Fly   165 ------------------------NISQPCNSMVIHCRFGADDYECARLFHPIVTDE-GLCCVFN 204
                                    |:|...|..|:.|.|.:.|....|.|...|..| |.|..||
 Worm   388 GAITTQTKENLIFLVAALPRETRRNLSYTLNEFVLRCSFNSKDCSMERDFKLHVDPEYGNCYTFN 452

  Fly   205 MLHPRFMYRKRVPYSHRNISLPEGFHAVNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSL 269
            .                           |...||...:.|       |:|           ||.|
 Worm   453 F---------------------------NDSVELKNSRAG-------PMY-----------GLRL 472

  Fly   270 TLDV-QADAYYCSSSSSIGFKIALHSPNESP------NVRETGVLLAPGMETKLRIDPSKILTEK 327
            .|:| |:|  |..::.:.|.::.:|..::.|      ....||.:.:.|::|            |
 Worm   473 LLNVHQSD--YMPTTEAAGVRLVVHEQDQEPFPDTFGYSAPTGFISSFGLKT------------K 523

  Fly   328 HLRNVDRRSRRC--------LFHNELKLRWFAHYTQRNCVAECLSGWLIRHCGC--VTFYMP--- 379
            .|..:......|        ..:||       ||:...|...|....::..|||  ..|.:|
 Worm   524 ELHRLSAPWGNCSDTFRPVPYIYNE-------HYSPEGCHRNCFQLKVLEICGCGDPRFPLPSEE 581

  Fly   380 --RLNANDTICPLHKRECVELIR-----FRTIIAMESCLDECLPSCFDLSFSAIAYSTRISLDGF 437
              ..||...|    .|:|:..:.     :..:.....|...|....|:.::||.|:.::    .|
 Worm   582 HRHCNAKSKI----DRQCLSNLTSDSGGYHHLHEQCECRQPCHEKVFETAYSASAWPSQ----NF 638

  Fly   438 R---ETPS-NGGWNFTDA---YVERSVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFL 495
            :   :.|: :..:|.|:|   |..::.|.:.:|::...|.:.|:|......:..|..||.:||::
 Worm   639 KIGTDCPAVSDIFNDTEACTEYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWI 703

  Fly   496 GFSFLSIAECVYFALIRPCRTC 517
            |||.::.||   ||.:. |..|
 Worm   704 GFSVITFAE---FAELF-CEIC 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	121/694 (17%)
unc-8	NP_001294293.1	ASC	100..719	CDD:295594	125/717 (17%)
		deg-1	107..716	CDD:273309	123/698 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820