Protein Alignment ppk8 and asic4

DIOPT Version :10

• Sequence 1: NP_001036260.3
• Gene: ppk8 / 318213
• FlyBaseID: FBgn0052792
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: XP_031749131.1
• Gene: asic4 / 100486325
• XenbaseID: XB-GENE-940165
• Length: 535
• Species: Xenopus tropicalis
• Alignment Length: 567
• Identity: 122/567 - (21%)
• Similarity: 214/567 - (37%)
• Gaps: 118/567 - (20%)

  Fly    37 RNTDEFCRNTTIHGLKYINNSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPE 101
            |:...|...:|:|||::|..:......:..:.:|.|..|...:|.:......:..:|.:..:|.|
 Frog    39 RDLAAFASTSTLHGLRHIFQTGRLGIKQSLWALAFLASLLFFLYQVAKCALYYLEHPHVTAVDEE 103

  Fly   102 LTSIANEPFPAVTICNLNQALAERVEHFS-NDSVEFAMLQLLCRRKVDVELVKTNDSRWE----- 160
            :  :....|||:||||:|     |..|.: .|...:.:..|......|.|..:.:|..::
 Frog   104 V--MGEMIFPAITICNIN-----RFRHSALTDPDIYHLANLTGLPPKDREGHRDSDLMYDDPDML 161

  Fly   161 EFILNISQPCNSMVIHCRFGADDYEC-ARLFHPIVTDEGLCCVFNMLHPRFMYRKRVPYSHRNIS 224
            :.:.........|:..|.|..|  .| |:.|..:.|..|.|..||.
 Frog   162 DIVNRTGHQLAEMLKSCNFSGD--SCSAQNFSVVFTRYGKCYTFNA------------------- 205

  Fly   225 LPEGFHAVNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYY------CSSS 283
                                      :..:|:.::..|...||.:.||:|.:.|.      ..:|
 Frog   206 --------------------------DKKHPKVSRQGGMGNGLEIMLDIQQEEYLPIWRETNETS 244

  Fly   284 SSIGFKIALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRC--LFHNELK 346
            ...|.::.:||.:|.|.:.:.|..::||.:|.:...      |:.:..:.:....|  ....|..
 Frog   245 FEAGIRVQIHSQDEPPYIHQMGFGVSPGFQTFVSCQ------EQRMTYLPQPWGNCRSSIPGEEF 303

  Fly   347 LRWFAHYTQRNCVAECLSGWLIRHCGCVTFYMPRLNANDTICPLHKRECVELIRFRTIIAMESCL 411
            |..::.|:...|..:|....:||.|.|...:||   .|:|||......|.:.|....:   |...
 Frog   304 LSGYSTYSISACRLQCEKEAVIRKCACRMVHMP---GNETICSPVMYMCADHILDNMV---EDTS 362

  Fly   412 DECLPSCFDLSFSAIAYSTRISLDGFRETPSNGG-------WNFTDAYVERSVAVVNMYFKDPTF 469
            ::|  || ....:...||..||:   ...|:.|.       :|..:.|:..:..|::::|:...:
 Frog   363 EKC--SC-PTPCNLTRYSKEISM---VRIPNKGSARYLARKYNKNETYIRENFLVLDIFFEALNY 421

  Fly   470 RANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAECV--YFALIR------------PCRTCSE- 519
            ...:|.:.......|..:||.||||:|.|||:|.|.:  .:.:||            |.:..||
 Frog   422 ETIEQKKAYDLPSLLGDIGGQMGLFIGASFLTILEILDYMYEVIRDKVKRVAGRKQSPAKKPSEN 486

  Fly   520 IRQLNQPRVHQMNLKRSPTPGNIRYISAADWFQAELAHQQPNNRQHF 566
            |..|    |...|..:||.....|:...     |......||:.:|:
 Frog   487 IATL----VMDDNKDQSPCEVRGRHPEG-----AYATTMLPNHHRHY 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk8	NP_001036260.3	ASC	42..508	CDD:459966	105/489 (21%)
asic4	XP_031749131.1	ENaC	39..514	CDD:273304	119/555 (21%)