Protein Alignment Tlk and Ulk3

DIOPT Version :10

• Sequence 1: NP_001138153.1
• Gene: Tlk / 318206
• FlyBaseID: FBgn0283657
• Length: 1489
• Species: Drosophila melanogaster
• Sequence 2: NP_082171.1
• Gene: Ulk3 / 71742
• MGIID: 1918992
• Length: 472
• Species: Mus musculus
• Alignment Length: 289
• Identity: 87/289 - (30%)
• Similarity: 147/289 - (50%)
• Gaps: 37/289 - (12%)

  Fly  1148 DRYLLLMLLGKGGFSEVHKAFDLKEQR-YVACKV---HQLNKDWKEDKKANYIKHALREYNIHKA 1208
            |.::|...||.|.::.|:||:..|:.| .||.|.   ..|||        ..:::.|.|..|.|.
Mouse    12 DGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNK--------ASVENLLTEIEILKG 68

  Fly  1209 LDHPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKTIPEREARSIIMQVVSALKYLNEIK 1273
            :.||.:|:|.| |:.|.::...::|:|.|.||..::...:.:||:.||..:.|:.|||::|:|..
Mouse    69 IRHPHIVQLKD-FQWDNDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERN 132

  Fly  1274 PPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFV 1338
              :.|.||||.||||:.... ..:|:.|||.::.|..  ::..|.:      .|:..|:.||  :
Mouse   133 --ISHLDLKPQNILLSSLEK-PHLKLADFGFAQHMSP--WDEKHVL------RGSPLYMAPE--M 184

  Fly  1339 VGKNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENTILKATEVQFSNKPTVSNEAK 1403
            |.:.  :..::||:||||||.|:.|:|:.||.......  |||. |.....::...:|.:|.:.:
Mouse   185 VCRR--QYDARVDLWSVGVILYEALFGQPPFASRSFSE--LEEK-IRSNRVIELPLRPQLSLDCR 244

  Fly  1404 SFIRGCL---AYRKEDRMDVFALARHEYI 1429
            ..::..|   ..|:....|.||   |.::
Mouse   245 DLLQRLLERDPARRISFKDFFA---HPWV 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tlk	NP_001138153.1	STKc_TLK	1161..1428	CDD:270892	82/273 (30%)
Ulk3	NP_082171.1	STKc_ULK3	18..269	CDD:271023	85/280 (30%)
		MIT_2	279..353	CDD:239147
		MIT	374..449	CDD:239121