Protein Alignment Tlk and Tlk1

DIOPT Version :9

• Sequence 1: NP_001138153.1
• Gene: Tlk / 318206
• FlyBaseID: FBgn0283657
• Length: 1489
• Species: Drosophila melanogaster
• Sequence 2: NP_001381947.1
• Gene: Tlk1 / 311118
• RGDID: 1310370
• Length: 766
• Species: Rattus norvegicus
• Alignment Length: 905
• Identity: 373/905 - (41%)
• Similarity: 496/905 - (54%)
• Gaps: 220/905 - (24%)

  Fly   576 GNTAGLRG--SHT--------GGGSKSPSSAQQQQTAAQQQGSGVATGG-------SAGGSAGNQ 623
            |:.|..|.  :||        |...:..|...::|...:.:.:|||||.       |.|..|...
  Rat    26 GSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVATGSTGSTGSCSVGAKASTN 90

  Fly   624 VQVQTSSAYALYPPASPQTQTSQQQQQQQPGSDFHYVNSSKAQQQQQRQQQQTSNQMVPPHVVVG 688
            .:....|..:|...:..:::|.:::|.:          ||:.::::...|.::|...     .:|
  Rat    91 NESSNHSFGSLGSLSDKESETPEKKQSE----------SSRGRKRKAESQNESSQGK-----SIG 140

  Fly   689 LGGHPLSLASIQQQTPLSQQQQQQQQQQQQQQLGPPTTSTASVVP-------THPHQLGSLGVVG 746
            ..||.:|                   ...:.|.|..::....:.|       :|.|...|
  Rat   141 GRGHKIS-------------------DYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPS----- 181

  Fly   747 MVGVGVGVGVGVNVGVGPPLPPPP-------PMAMPAAIITYSKATQTEVSLHEL------QERE 798
                         ..|.|..|.|.       |:..|..:  ..|.|||::::.:|      :.::
  Rat   182 -------------SSVRPNSPSPTALAFGDHPVVQPKQL--SFKITQTDLTMLKLAALESTKNQD 231

  Fly   799 AEHESGKVKLDEMTRLSDEQKSQIVGNQKTIDQHKCHIAKCIDVVKKLLKEKSSIEKKEARQKCM 863
            .|.:.|::  |::.|.:.:.:.||...||.::::|..:.|||.:.||||.|||:.||..:|:|.|
  Rat   232 LEKKEGRI--DDLLRANCDLRRQIDDQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSM 294

  Fly   864 QNRLRLGQFVTQRVGATFQENWTDGYAFQELSRRQEEITAEREEIDRQKKQLMKKRPAESGRKRN 928
            |:|||||.|.|.|.||:|.|.||||:|||.|.::||.:..:||:|:||:|.|.|::|..:
  Rat   295 QDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTA----- 354

  Fly   929 NNSNQNNQQQQQQQHQQQQQQQNSNSNDSTQLTSGVVTGPGSDRVSVSVDSGLGGNNAGAIGGGT 993
            |||      |....:.:.:|::|...|
  Rat   355 NNS------QAPATNSEPKQRKNKAVN-------------------------------------- 375

  Fly   994 VGGGVGGGGVGGGGVGGGGGRGLSRSNSTQANQAQLLHNGGGGSGGNVGNSGGVGDRLSDRGGGG 1058
                                 |.......:.|..|||
  Rat   376 ---------------------GAENDPFVRPNLPQLL---------------------------- 391

  Fly  1059 GGIGGNDSGSCSDSGTFLKPDPVSGAYTAQEYYEYDEILKLRQNALKKEDADLQLEMEKLERERN 1123
                                       |..||:|.:||.|||...||||:|::|.|:|:|||.||
  Rat   392 ---------------------------TLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRN 429

  Fly  1124 LHIRELKRILNEDQSRFNNHPVLNDRYLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWK 1188
            |||||||||.|||.|:|.:||.||:|||||.|||:||||||:|||||.||||.|.|:|||||.|:
  Rat   430 LHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWR 494

  Fly  1189 EDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKTIPER 1253
            ::||.||.|||.|||.|||.|||||:|||||.|.:|.::||||||||:|:||||||||||.:.|:
  Rat   495 DEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEK 559

  Fly  1254 EARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHG 1318
            |||||:||:|:||:||||||||:||||||||||||.:|..|||||||||||||:|||::|..| |
  Rat   560 EARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVD-G 623

  Fly  1319 MDLTSQGAGTYWYLPPECFVVGKNPPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENT 1383
            |||||||||||||||||||||||.|||||:|||||||||||:|||||:|||||||||..||:|||
  Rat   624 MDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENT 688

  Fly  1384 ILKATEVQFSNKPTVSNEAKSFIRGCLAYRKEDRMDVFALARHEYIQPPIPK-HGRGSLN 1442
            |||||||||..||.||:|||:|||.|||||||||.||..||...|:.|.:.: :..|:|:
  Rat   689 ILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLH 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tlk	NP_001138153.1	S_TKc	1161..1429	CDD:214567	206/267 (77%)
		STKc_TLK	1161..1428	CDD:270892	206/266 (77%)
Tlk1	NP_001381947.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354371
Domainoid	1	1.000	462	1.000	Domainoid score	I456
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001851
OrthoInspector	1	1.000	-	-		otm44472
orthoMCL	1	0.900	-	-		OOG6_101432
Panther	1	1.100	-	-	LDO	PTHR22974
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1213
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.840