Protein Alignment Tlk and tlk1

DIOPT Version :10

• Sequence 1: NP_001138153.1
• Gene: Tlk / 318206
• FlyBaseID: FBgn0283657
• Length: 1489
• Species: Drosophila melanogaster
• Sequence 2: XP_002934666.2
• Gene: tlk1 / 100144941
• XenbaseID: XB-GENE-1002113
• Length: 716
• Species: Xenopus tropicalis
• Alignment Length: 881
• Identity: 370/881 - (41%)
• Similarity: 482/881 - (54%)
• Gaps: 216/881 - (24%)

  Fly   581 LRGSHTGGGSKSPSSAQQQQTAAQQQGSGVATGGSAGGSAGNQVQVQTSSAYALYPPASPQTQTS 645
            |....|||.|                ||..:||.|.|..|.|    ..||.::.....|...:.|
 Frog    15 LEARFTGGVS----------------GSTGSTGSSVGAKASN----NESSNHSFGSLGSLSDKES 59

  Fly   646 QQQQQQQPGSDFHYVNSSKAQQQQQRQQQQTSNQMVPPHVVVGLGGHPLSLASIQQQTPLSQQQQ 710
            :..:::||.|.    ...|.:.:.|.:..|..|.        |..||.:|
 Frog    60 ETPEKKQPDSS----RGRKRKAENQSESSQGKNS--------GGRGHKIS--------------- 97

  Fly   711 QQQQQQQQQQLGPPTTSTASVVP-------THPHQLGSLGVVGMVGVGVGVGVGVNVGVGPPLPP 768
                .....|.|..|:....:.|       :|.|...|                  .......|.
 Frog    98 ----DYFDYQAGNGTSPVRGLPPSIRSPQNSHSHSTPS------------------SSARQNSPS 140

  Fly   769 PPPMAMPAAIITYS-----KATQTEVSLHEL------QEREAEHESGKVKLDEMTRLSDEQKSQI 822
            |..:|....:::.:     |..||::::.:|      :.::.|.:.|::  |::.|.:.:.:.||
 Frog   141 PTALAFGDHLLSQTKQLSYKLVQTDLTMLKLAALESNKNQDLEKKEGRI--DDLLRTNCDLRRQI 203

  Fly   823 VGNQKTIDQHKCHIAKCIDVVKKLLKEKSSIEKKEARQKCMQNRLRLGQFVTQRVGATFQENWTD 887
            ...||.::::|..:.|||.:.||||.|||:.||..:|:|.||:|||||.|.|.|.||:|.|.|||
 Frog   204 DEQQKILEKYKERLNKCISMSKKLLIEKSTQEKLASREKSMQDRLRLGHFTTVRHGASFTEQWTD 268

  Fly   888 GYAFQELSRRQEEITAEREEIDRQKKQLMKKRPAESGRKRNNNSNQNNQQQQQQQHQQQQQQQNS 952
            |:|||.|.::||.:..:||:|:||:|||.|::|..|           |..|....:.:.:|::|.
 Frog   269 GFAFQNLVKQQEWVNQQREDIERQRKQLAKRKPPSS-----------NSSQTPSANSEPKQRKNK 322

  Fly   953 NSNDSTQLTSGVVTGPGSDRVSVSVDSGLGGNNAGAIGGGTVGGGVGGGGVGGGGVGGGGGRGLS 1017
                                               |:.|
 Frog   323 -----------------------------------AVNG-------------------------- 326

  Fly  1018 RSNSTQANQAQLLHNGGGGSGGNVGNSGGVGDRLSDRGGGGGGIGGNDSGSCSDSGTFLKPDPVS 1082
                                                                :::..|:||. :.
 Frog   327 ----------------------------------------------------AENDPFVKPS-LP 338

  Fly  1083 GAYTAQEYYEYDEILKLRQNALKKEDADLQLEMEKLERERNLHIRELKRILNEDQSRFNNHPVLN 1147
            ...|..||:|.:||.|||...||||:|::|.|:|:|||.|||||||||||.|||.|:|.:||.||
 Frog   339 QLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLN 403

  Fly  1148 DRYLLLMLLGKGGFSEVHKAFDLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHP 1212
            :|||||.|||:||||||:|||||.||||.|.|:|||||.|:::||.||.|||.|||.|||.||||
 Frog   404 ERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHP 468

  Fly  1213 RVVKLYDVFEIDANSFCTVLEYCDGHDLDFYLKQHKTIPEREARSIIMQVVSALKYLNEIKPPVI 1277
            |:|||||.|.:|.::||||||||:|:||||||||||.:.|:|||||:||:|:||:||||||||:|
 Frog   469 RIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPII 533

  Fly  1278 HYDLKPGNILLTEGNVCGEIKITDFGLSKVMDDENYNPDHGMDLTSQGAGTYWYLPPECFVVGKN 1342
            |||||||||||.:|..|||||||||||||:|||::|..| ||||||||||||||||||||||||.
 Frog   534 HYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVD-GMDLTSQGAGTYWYLPPECFVVGKE 597

  Fly  1343 PPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENTILKATEVQFSNKPTVSNEAKSFIR 1407
            |||||:|||||||||||:|||||:|||||||||..||:||||||||||||..||.||||||:|||
 Frog   598 PPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSNEAKAFIR 662

  Fly  1408 GCLAYRKEDRMDVFALARHEYIQPPIPK-HGRGSLN 1442
            .|||||||||.||..||...|:.|.:.: :..|:|:
 Frog   663 RCLAYRKEDRFDVHQLANDAYLLPHMRRSNSSGNLH 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tlk	NP_001138153.1	STKc_TLK	1161..1428	CDD:270892	207/266 (78%)
tlk1	XP_002934666.2	EnvC	152..>376	CDD:443969	89/350 (25%)
		STKc_TLK1	399..697	CDD:270942	224/298 (75%)