Protein Alignment HNRNPAB and HRP1

DIOPT Version :9

• Sequence 1: NP_112556.2
• Gene: HNRNPAB / 3182
• HGNCID: 5034
• Length: 332
• Species: Homo sapiens
• Sequence 2: NP_014518.1
• Gene: HRP1 / 853997
• SGDID: S000005483
• Length: 534
• Species: Saccharomyces cerevisiae
• Alignment Length: 347
• Identity: 110/347 - (31%)
• Similarity: 171/347 - (49%)
• Gaps: 58/347 - (16%)

Human    11 ETTGATENGHEAVPEG-------ESPAGAGTGAAAGAGGATAAPPSG----------------NQ 52
            :|:.:.::|.....||       |....:.|.|.|.| .|::|.|||                :.
Yeast    71 DTSSSKQDGTANDKEGSNEDTKNEKKQESATSANANA-NASSAGPSGLPWEQLQQTMSQFQQPSS 134

Human    53 NGAEGDQINASKNE-------EDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRS 110
            ......|:..:|.|       :::.|||:|||:|||::.:|::||.|:|.|.|..|..||.||||
Yeast   135 QSPPQQQVTQTKEERSKADLSKESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRS 199

Human   111 RGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAM-KKDPVKKIFVGGLNPEATEEKIREYF 174
            |||||:.|:..:||::|: :.:|.|||:|||||:|:.. ::|...||||||:.|:...::..|:|
Yeast   200 RGFGFLSFEKPSSVDEVV-KTQHILDGKVIDPKRAIPRDEQDKTGKIFVGGIGPDVRPKEFEEFF 263

Human   175 GEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQ 239
            .::|.|...:|.:|....:.|||.|:|:...:.|.:|.:.||......|.|||.|:|:.:.|:..
Yeast   264 SQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRVCQNKFIDFKDRKIEIKRAEPRHMQQKSS 328

Human   240 YGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYD--YSPYGYYG 302
            ...|..|..|...||                  ||:.|||...|....|..|||:  .:|.....
Yeast   329 NNGGNNGGNNMNRRG------------------GNFGNQGDFNQMYQNPMMGGYNPMMNPQAMTD 375

Human   303 YGPGYDYSQGSTNYGKSQRRGG 324
            |     |.:....|.:.|::.|
Yeast   376 Y-----YQKMQEYYQQMQKQTG 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HNRNPAB	NP_112556.2	CBFNT	1..70	CDD:311868	17/88 (19%)
		RRM1_hnRNPAB	66..145	CDD:410151	42/85 (49%)
		RRM2_hnRNPAB	150..229	CDD:409997	27/78 (35%)
HRP1	NP_014518.1	PABP-1234	<144..463	CDD:130689	95/273 (35%)
		RRM1_Hrp1p	161..236	CDD:409991	41/75 (55%)
		RRM2_Hrp1p	244..321	CDD:409767	27/76 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I2313
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I1143
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.960