Protein Alignment HNRNPAB and CG4612

DIOPT Version :9

• Sequence 1: NP_112556.2
• Gene: HNRNPAB / 3182
• HGNCID: 5034
• Length: 332
• Species: Homo sapiens
• Sequence 2: NP_001246493.1
• Gene: CG4612 / 37914
• FlyBaseID: FBgn0035016
• Length: 307
• Species: Drosophila melanogaster
• Alignment Length: 249
• Identity: 66/249 - (26%)
• Similarity: 119/249 - (47%)
• Gaps: 39/249 - (15%)

Human    18 NGHEAVPEGE---SPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSW 79
            :||.::..|.   |...|..|...| |||.|   ||:..|:.|:      :..|:||:::..|..
  Fly    68 HGHNSLGSGHTSTSSHSANVGVGVG-GGALA---SGSTGGSGGN------SSPDSGKIYIKNLER 122

Human    80 DTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD----AASVEKV-----LDQKEHRL 135
            ....|.:.|.|:.||.:::|.:..|.: |.|||:||:.|..    .|::|||     .:||.|.:
  Fly   123 SIDNKAVYDTFSVFGNILNCNVAKDED-GNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVV 186

Human   136 DGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFI 200
              :.|..:.....|....|.::|..|:.|.||:.:||.|..:|.|.:.:|.:|.:...|| |.|:
  Fly   187 --KFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRR-FGFV 248

Human   201 TFKEEEPV---------KKVLEKKF----HTVSGSKCEIKVAQPKEVYQQQQYG 241
            .::..:..         |::.:.||    ..:|.::.:.::.:..|..::|:.|
  Fly   249 AYENPQSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQKAG 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HNRNPAB	NP_112556.2	CBFNT	1..70	CDD:311868	16/54 (30%)
		RRM1_hnRNPAB	66..145	CDD:410151	26/87 (30%)
		RRM2_hnRNPAB	150..229	CDD:409997	21/91 (23%)
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	21/70 (30%)
		RRM3_I_PABPs	202..282	CDD:240826	20/80 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	2	1.870