DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and Tmprss5

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001346389.1	Gene:	Tmprss5 / 80893	MGIID:	1933407	Length:	455	Species:	Mus musculus

Alignment Length:	251	Identity:	89/251 - (35%)
Similarity:	128/251 - (50%)	Gaps:	35/251 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHC-YAINTSVPLVYRD 100
            :||||..|...:.|:|.||.        .|..|.||.:|::...|.:|||| |:...|....:|
Mouse   217 RIVGGQAVASGRWPWQASVM--------LGSRHTCGASVLAPHWVVTAAHCMYSFRLSRLSSWR- 272

  Fly   101 PELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPW-ESPGVRAIPL 164
              ::..:....|:    |..|..:|::|:.|..|:....:.|:|||.|...|.: ::.|...:|
Mouse   273 --VHAGLVSHGAV----RQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVGAVCLP- 330

  Fly   165 AIKAPEE----GTTCLIHGWGKV--TMKEKSASLQQAPVPILNKELC--QVIYK--LPASQMCAG 219
               |.|:    |:.|.:.|||..  :....|.:||...||:|:..||  ..:|.  |....:|||
Mouse   331 ---AKEQHFPWGSQCWVSGWGHTDPSHTHSSDTLQDTMVPLLSTYLCNSSCMYSGALTHRMLCAG 392

  Fly   220 FLQGGIDACQGDSGGPLICDG----RLAGIISWGVGCADPGYPGVYTNVSHFLKWI 271
            :|.|..|||||||||||:|..    .|.|::|||.|||:|..||||..|:.||.||
Mouse   393 YLDGRADACQGDSGGPLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWI 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	87/249 (35%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	89/250 (36%)
Tmprss5	NP_001346389.1	SRCR_2	116..213	CDD:317845
Tmprss5	NP_001346389.1	Tryp_SPc	217..448	CDD:214473	87/249 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010