DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and prss60.1

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	281	Identity:	100/281 - (35%)
Similarity:	139/281 - (49%)	Gaps:	44/281 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCY-AINTSVPLVYRD 100
            :||||........|:||     |:|...|| ||.|||::|:...|.:||||. .|.||..||:
Zfish    33 RIVGGVNAFDGSWPWQV-----SLHSPIYG-GHFCGGSLINSEWVLTAAHCLPRITTSSLLVF-- 89

  Fly   101 PELYVVVAGSSAIDRTDRFTQEYLVQRIVG----HKDYNGSTLENDIALLFLNGFIPWESPGVRA 161
                   .|.:    |.:....|.:.|.|.    |..||..|.|||||||.|:..:.: |..:|.
Zfish    90 -------LGKT----TQQGVNTYEINRTVSVITVHPSYNNLTNENDIALLHLSSAVTF-SNYIRP 142

  Fly   162 IPLAIKAP--EEGTTCLIHGWGKVTMKEKSAS---LQQAPVPILNKELCQVIY---KLPASQMCA 218
            :.||.:..  ..||:..|.|||.:.:.....:   ||:..:|::..:.|..:.   .:..:.:||
Zfish   143 VCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQCNALLGSGSVTNNMICA 207

  Fly   219 GFLQGGIDACQGDSGGPLICDGRL----AGIISWGVGCADPGYPGVYTNVSHFLKWIRRANASLD 279
            |.||||.|.||||||||::....|    :||.|||.|||||..|||||.||.:..||   |:.:
Zfish   208 GLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSWGYGCADPYSPGVYTRVSQYQSWI---NSII- 268

  Fly   280 YSEYRQIPPLNLASRRSVSSS 300
               .:.:|...|.:..|..||
Zfish   269 ---VQNLPGFVLFNSSSTCSS 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	92/250 (37%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	94/251 (37%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	92/250 (37%)
		Tryp_SPc	34..267	CDD:238113	95/255 (37%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910