DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and tmprss4a

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_005157547.1	Gene:	tmprss4a / 777630	ZFINID:	ZDB-GENE-061103-631	Length:	458	Species:	Danio rerio

Alignment Length:	247	Identity:	86/247 - (34%)
Similarity:	128/247 - (51%)	Gaps:	33/247 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYRDP 101
            :||||....|...|:|||::        |...|.|||::::...|.:||||:..:....|
Zfish   223 RIVGGKDADIANWPWQVSLQ--------YSGQHTCGGSLVTPNWVVTAAHCFNGDGRKAL----- 274

  Fly   102 ELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPW-ESPGVRAIP-- 163
            ..:.||:|.:.:..|   ...| |:.|:.:.:|..:..:.||.::.|...|.. ||.....:|
Zfish   275 SRWTVVSGITYLSST---PSSY-VKEIIVNSNYKPAESDFDITMIKLQSPITLSESRRPVCLPPQ 335

  Fly   164 -LAIKAPEEGTTCLIHGWGKVTMKEKSAS--LQQAPVPILNKELCQ--VIY--KLPASQMCAGFL 221
             |.:|.   |...::.|||.:..|..|.|  ||:|.:.:::...|.  .:|  .:....:|||.:
Zfish   336 NLGLKG---GDGLVVTGWGHMAEKGGSLSSMLQKAQIQVIDSAQCSSPTVYGSSITPRMICAGVM 397

  Fly   222 QGGIDACQGDSGGPLI--CD-GRLAGIISWGVGCADPGYPGVYTNVSHFLKW 270
            .||:|||||||||||:  .| ..|.|::|||||||.||:|||||||...|.|
Zfish   398 AGGVDACQGDSGGPLVHLADRWVLVGVVSWGVGCARPGFPGVYTNVDQMLDW 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	86/247 (35%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	86/246 (35%)
tmprss4a	XP_005157547.1	LDLa	74..105	CDD:238060
		SRCR_2	121..218	CDD:295335
		Tryp_SPc	223..449	CDD:214473	85/245 (35%)
		Tryp_SPc	224..449	CDD:238113	85/244 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010