DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and ST14

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_068813.1	Gene:	ST14 / 6768	HGNCID:	11344	Length:	855	Species:	Homo sapiens

Alignment Length:	305	Identity:	99/305 - (32%)
Similarity:	138/305 - (45%)	Gaps:	59/305 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HLWMCLLIVATHSGITQSQIGQPTATAS-----------------PFVILPKIVGGYTVTIDQVP 50
            |.:.||      :|:..|: |.|.....                 .|....::|||......:.|
Human   570 HTYRCL------NGLCLSK-GNPECDGKEDCSDGSDEKDCDCGLRSFTRQARVVGGTDADEGEWP 627

  Fly    51 FQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYRDPELYVVVAGSSAIDR 115
            :|||:..       .|.||:||.::||...:.||||||..:..  ..|.||..:....|..  |:
Human   628 WQVSLHA-------LGQGHICGASLISPNWLVSAAHCYIDDRG--FRYSDPTQWTAFLGLH--DQ 681

  Fly   116 TDRF---TQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWESPG-----VRAI--PLAIKAPE 170
            :.|.   .||..::||:.|..:|..|.:.|||||.|      |.|.     ||.|  |.|.....
Human   682 SQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLEL------EKPAEYSSMVRPICLPDASHVFP 740

  Fly   171 EGTTCLIHGWGKVTMKEKSA-SLQQAPVPILNKELCQVI--YKLPASQMCAGFLQGGIDACQGDS 232
            .|....:.|||........| .||:..:.::|:..|:.:  .::....||.|||.||:|:|||||
Human   741 AGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQITPRMMCVGFLSGGVDSCQGDS 805

  Fly   233 GGPLI---CDGRL--AGIISWGVGCADPGYPGVYTNVSHFLKWIR 272
            ||||.   .|||:  ||::|||.|||....|||||.:..|..||:
Human   806 GGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIK 850

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	89/251 (35%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	91/253 (36%)
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SEA	88..>171	CDD:307516
		CUB	227..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	488..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060	7/38 (18%)
		Tryp_SPc	615..852	CDD:238113	91/253 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910