DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32755 and PRSS56

DIOPT Version :9

Sequence 1:	NP_727055.1	Gene:	CG32755 / 318192	FlyBaseID:	FBgn0052755	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001356777.1	Gene:	PRSS56 / 646960	HGNCID:	39433	Length:	604	Species:	Homo sapiens

Alignment Length:	280	Identity:	92/280 - (32%)
Similarity:	142/280 - (50%)	Gaps:	49/280 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KIVGGYTVTIDQVPFQVSVRRRSIHERHYGLGHVCGGAVISQRVVCSAAHCYAINTSVPLVYRDP 101
            :||||........|:.|.::        .|...:|||.:::...|.:||||: :.....|::.
Human   104 RIVGGSAAPPGAWPWLVRLQ--------LGGQPLCGGVLVAASWVLTAAHCF-VGAPNELLWT-- 157

  Fly   102 ELYVVVAGSSAIDRTDRFTQEYLVQRIVGHKDYNGSTLENDIALLFLNGFIPWE--SPGVRAIPL 164
               |.:|..|..::    .:|..|.||:.|..::..|..||:||:.|     |.  |||..|.|:
Human   158 ---VTLAEGSRGEQ----AEEVPVNRILPHPKFDPRTFHNDLALVQL-----WTPVSPGGSARPV 210

  Fly   165 AI----KAPEEGTTCLIHGWGKVTMKEKSA-SLQQAPVPILNKELCQVIY---KLPASQMCAGFL 221
            .:    :.|..||.|.|.|||.:......| ::::|.||:|:.:.|:...   ..|::.:|||:|
Human   211 CLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYL 275

  Fly   222 QGGIDACQGDSGGPLICDGR-------LAGIISWGVGCADPGYPGVYTNVSHFLKWIRR----AN 275
            .||:|:|||||||||.|...       |.|:.|||.||.:||.|||||.|:.|..|::.    |:
Human   276 AGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAAS 340

  Fly   276 ASLDYSEYRQI----PPLNL 291
            :|.:.| .|::    ||..|
Human   341 SSREPS-CRELLAWDPPQEL 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32755	NP_727055.1	Tryp_SPc	37..271	CDD:214473	84/250 (34%)
CG32755	NP_727055.1	Tryp_SPc	38..273	CDD:238113	85/251 (34%)
PRSS56	NP_001356777.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	64..96
		Tryp_SPc	105..335	CDD:238113	85/252 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	443..475
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	574..604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910